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SGD:RAD18
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | RAD18 ( synonyms: YCR066W ) | |
| Protein Name(s) | E3 ubiquitin ligase, | |
| External Links | ||
| SGD | S000000662 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000790 |
nuclear chromatin |
SGD_REF:S000042429 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0003676 |
nucleic acid binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From SGD |
||
| GO:0003684 |
damaged DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003697 |
single-stranded DNA binding |
SGD_REF:S000054293 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000054293 |
IPI: Inferred from Physical Interaction |
SGD:S000003026 |
F |
From SGD |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000071479 |
IPI: Inferred from Physical Interaction |
SGD:S000000292 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000042429 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006281 |
DNA repair |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From SGD |
||
| GO:0006513 |
protein monoubiquitination |
SGD_REF:S000071479 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006974 |
response to DNA damage stimulus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From SGD |
||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016874 |
ligase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From SGD |
||
| GO:0042275 |
error-free postreplication DNA repair |
SGD_REF:S000049026 |
IGI: Inferred from Genetic Interaction |
SGD:S000003055 |
P |
From SGD |
||
| GO:0042275 |
error-free postreplication DNA repair |
SGD_REF:S000052178 |
IGI: Inferred from Genetic Interaction |
SGD:S000004022 |
P |
From SGD |
||
| GO:0042276 |
error-prone translesion synthesis |
SGD_REF:S000069717 |
IGI: Inferred from Genetic Interaction |
SGD:S000006088 |
P |
From SGD |
||
| GO:0042276 |
error-prone translesion synthesis |
SGD_REF:S000080631 |
IGI: Inferred from Genetic Interaction |
SGD:S000005943 |
P |
From SGD |
||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0070987 |
error-free translesion synthesis |
SGD_REF:S000041995 |
IGI: Inferred from Genetic Interaction |
SGD:S000002827 |
P |
From SGD |
||
|
contributes_to |
GO:0043142 |
single-stranded DNA-dependent ATPase activity |
SGD_REF:S000051450 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ulrich HD & Jentsch S (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 19: 3388-97 PubMed GONUTS page
- ↑ 2.0 2.1 Bailly V et al. (1994) Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites. Genes Dev 8: 811-20 PubMed GONUTS page
- ↑ 3.0 3.1 Hoege C et al. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419: 135-41 PubMed GONUTS page
- ↑ Broomfield S et al. (1998) MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway. Proc Natl Acad Sci U S A 95: 5678-83 PubMed GONUTS page
- ↑ Xiao W et al. (2000) The Saccharomyces cerevisiae RAD6 group is composed of an error-prone and two error-free postreplication repair pathways. Genetics 155: 1633-41 PubMed GONUTS page
- ↑ Huang ME et al. (2002) Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway. Genetics 160: 1409-22 PubMed GONUTS page
- ↑ Minesinger BK & Jinks-Robertson S (2005) Roles of RAD6 epistasis group members in spontaneous polzeta-dependent translesion synthesis in Saccharomyces cerevisiae. Genetics 169: 1939-55 PubMed GONUTS page
- ↑ McDonald JP et al. (1997) The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism. Genetics 147: 1557-68 PubMed GONUTS page
- ↑ Bailly V et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272: 23360-5 PubMed GONUTS page
