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SGD:RAD1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) RAD1 ( synonyms: YPL022W, LPB9 )
Protein Name(s) Single-stranded DNA endonuclease (with Rad10p),
External Links
SGD S000005943

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000110

nucleotide-excision repair factor 1 complex

SGD_REF:S000053761
PMID:8621533[1]

IPI: Inferred from Physical Interaction

SGD:S000004560
SGD:S000004814

C

From SGD

GO:0000710

meiotic mismatch repair

SGD_REF:S000061201
PMID:11514439[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000712

resolution of meiotic recombination intermediates

SGD_REF:S000146947

PANTHER:PTHR10150_AN0

P

From SGD

GO:0000724

double-strand break repair via homologous recombination

SGD_REF:S000146947

PANTHER:PTHR10150_AN0

P

From SGD

GO:0000735

removal of nonhomologous ends

SGD_REF:S000046045
PMID:7891718[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000735

removal of nonhomologous ends

SGD_REF:S000051157
PMID:1411547[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000736

double-strand break repair via single-strand annealing, removal of nonhomologous ends

SGD_REF:S000046045
PMID:7891718[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000736

double-strand break repair via single-strand annealing, removal of nonhomologous ends

SGD_REF:S000051157
PMID:1411547[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006167

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006166
InterPro:IPR020819

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003697

single-stranded DNA binding

SGD_REF:S000046088
PMID:8253764[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006166
InterPro:IPR020819

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From SGD

GO:0004519

endonuclease activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006167

F

From SGD

GO:0004519

endonuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0255

F

From SGD

GO:0005634

nucleus

SGD_REF:S000047071
PMID:9852079[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006259

DNA metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006166
InterPro:IPR020819

P

From SGD

GO:0006281

DNA repair

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006167

P

From SGD

GO:0006281

DNA repair

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From SGD

GO:0006296

nucleotide-excision repair, DNA incision, 5'-to lesion

SGD_REF:S000045969
PMID:7559571[7]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006312

mitotic recombination

SGD_REF:S000052152
PMID:3065620[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0090305

nucleic acid phosphodiester bond hydrolysis

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006166
InterPro:IPR020819

P

From SGD

contributes_to

GO:0000014

single-stranded DNA specific endodeoxyribonuclease activity

SGD_REF:S000046088
PMID:8253764[5]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Guzder SN et al. (1996) Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome. J Biol Chem 271: 8903-10 PubMed GONUTS page
  2. Kearney HM et al. (2001) Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. Genetics 158: 1457-76 PubMed GONUTS page
  3. 3.0 3.1 Ivanov EL & Haber JE (1995) RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 15: 2245-51 PubMed GONUTS page
  4. 4.0 4.1 Fishman-Lobell J & Haber JE (1992) Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science 258: 480-4 PubMed GONUTS page
  5. 5.0 5.1 Sung P et al. (1993) Purification and characterization of the Saccharomyces cerevisiae RAD1/RAD10 endonuclease. J Biol Chem 268: 26391-9 PubMed GONUTS page
  6. Rodriguez K et al. (1998) Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein. J Biol Chem 273: 34180-9 PubMed GONUTS page
  7. Davies AA et al. (1995) Role of the Rad1 and Rad10 proteins in nucleotide excision repair and recombination. J Biol Chem 270: 24638-41 PubMed GONUTS page
  8. Schiestl RH & Prakash S (1988) RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol Cell Biol 8: 3619-26 PubMed GONUTS page
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