Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

SGD:POL3

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) POL3 ( synonyms: YDL102W, CDC2, HPR6, TEX1 )
Protein Name(s) Catalytic subunit of DNA polymerase delta,
External Links
SGD S000002260

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000084

S phase of mitotic cell cycle

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

P

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR004578
InterPro:IPR006134
InterPro:IPR017964
InterPro:IPR006172

F

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006172
InterPro:IPR017964
InterPro:IPR012337

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006134
InterPro:IPR004578

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000040127
PMID:1678279[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000040127
PMID:1678279[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006133
InterPro:IPR006172
InterPro:IPR006134
InterPro:IPR004578
InterPro:IPR017964

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.7

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000127057
PMID:18635534[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0239

F

From SGD

GO:0004518

nuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From SGD

GO:0004527

exonuclease activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005657

replication fork

SGD_REF:S000081149
PMID:15773893[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006139

nucleobase-containing compound metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR017964
InterPro:IPR006172

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000040127
PMID:1678279[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006134
InterPro:IPR006133
InterPro:IPR004578

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0235

P

From SGD

GO:0006272

leading strand elongation

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

P

From SGD

GO:0006273

lagging strand elongation

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

P

From SGD

GO:0006278

RNA-dependent DNA replication

SGD_REF:S000122326
PMID:17429354[5]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006284

base-excision repair

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

P

From SGD

GO:0006287

base-excision repair, gap-filling

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

P

From SGD

GO:0006289

nucleotide-excision repair

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

P

From SGD

GO:0006297

nucleotide-excision repair, DNA gap filling

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

P

From SGD

GO:0006298

mismatch repair

SGD_REF:S000058372
PMID:9745046[4]

NAS: Non-traceable Author Statement

P

From SGD

GO:0006298

mismatch repair

SGD_REF:S000058456
PMID:10072354[6]

NAS: Non-traceable Author Statement

P

From SGD

GO:0006301

postreplication repair

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

P

From SGD

GO:0007346

regulation of mitotic cell cycle

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

P

From SGD

GO:0008296

3'-5'-exodeoxyribonuclease activity

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

F

From SGD

GO:0008310

single-stranded DNA specific 3'-5' exodeoxyribonuclease activity

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

F

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016779

nucleotidyltransferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0548

F

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0043137

DNA replication, removal of RNA primer

SGD_REF:S000117063
PMID:16837458[7]

IDA: Inferred from Direct Assay

P

From SGD

GO:0043625

delta DNA polymerase complex

SGD_REF:S000058372
PMID:9745046[4]

TAS: Traceable Author Statement

C

From SGD

GO:0043625

delta DNA polymerase complex

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

C

From SGD

GO:0045004

DNA replication proofreading

SGD_REF:S000146947

PANTHER:PTHR10322_AN133

P

From SGD

GO:0045005

maintenance of fidelity involved in DNA-dependent DNA replication

SGD_REF:S000079974
PMID:15601866[8]

IGI: Inferred from Genetic Interaction

SGD:S000005450
SGD:S000001596
SGD:S000005559

P

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Blank A & Loeb LA (1991) Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2. Biochemistry 30: 8092-6 PubMed GONUTS page
  2. Langston LD & O'Donnell M (2008) DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. J Biol Chem 283: 29522-31 PubMed GONUTS page
  3. Hiraga S et al. (2005) DNA polymerases alpha, delta, and epsilon localize and function together at replication forks in Saccharomyces cerevisiae. Genes Cells 10: 297-309 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107: 218-27 PubMed GONUTS page
  5. Storici F et al. (2007) RNA-templated DNA repair. Nature 447: 338-41 PubMed GONUTS page
  6. Kolodner RD & Marsischky GT (1999) Eukaryotic DNA mismatch repair. Curr Opin Genet Dev 9: 89-96 PubMed GONUTS page
  7. Rossi ML & Bambara RA (2006) Reconstituted Okazaki fragment processing indicates two pathways of primer removal. J Biol Chem 281: 26051-61 PubMed GONUTS page
  8. Jin YH et al. (2005) The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Mol Cell Biol 25: 461-71 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox