Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

SGD:POL1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) POL1 ( synonyms: YNL102W, CDC17, CRT5, HPR3 )
Protein Name(s) Catalytic subunit of the DNA polymerase I alpha-primase complex,
External Links
SGD S000005046

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000076

DNA replication checkpoint

SGD_REF:S000146947

PANTHER:PTHR10322_AN3

P

From SGD

GO:0000084

S phase of mitotic cell cycle

SGD_REF:S000146947

PANTHER:PTHR10322_AN3

P

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR017964
InterPro:IPR006172
InterPro:IPR004578
InterPro:IPR006134

F

From SGD

GO:0000731

DNA synthesis involved in DNA repair

SGD_REF:S000056091
PMID:10025407[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000731

DNA synthesis involved in DNA repair

SGD_REF:S000056892
PMID:2651896[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000734

gene conversion at mating-type locus, DNA repair synthesis

SGD_REF:S000146947

PANTHER:PTHR10322_AN45

P

From SGD

GO:0001882

nucleoside binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR015088

F

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR017964
InterPro:IPR012337
InterPro:IPR006172

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006134
InterPro:IPR004578

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000064604
PMID:3907855[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000064605
PMID:3888995[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000116439
PMID:1704371[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006172
InterPro:IPR017964
InterPro:IPR015088
InterPro:IPR006133
InterPro:IPR004578
InterPro:IPR006134

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.7

F

From SGD

GO:0003887

DNA-directed DNA polymerase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0239

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005657

replication fork

SGD_REF:S000081149
PMID:15773893[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005658

alpha DNA polymerase:primase complex

SGD_REF:S000064605
PMID:3888995[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006139

nucleobase-containing compound metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR017964
InterPro:IPR006172

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000056892
PMID:2651896[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006134
InterPro:IPR006133
InterPro:IPR004578
InterPro:IPR015088

P

From SGD

GO:0006260

DNA replication

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0235

P

From SGD

GO:0006269

DNA replication, synthesis of RNA primer

SGD_REF:S000146947

PANTHER:PTHR10322_AN3

P

From SGD

GO:0006270

DNA-dependent DNA replication initiation

SGD_REF:S000064605
PMID:3888995[4]

IC: Inferred by Curator

GO:0005658

P

From SGD

GO:0006271

DNA strand elongation involved in DNA replication

SGD_REF:S000146947

PANTHER:PTHR10322_AN3

P

From SGD

GO:0006273

lagging strand elongation

SGD_REF:S000064605
PMID:3888995[4]

IC: Inferred by Curator

GO:0005658

P

From SGD

GO:0006278

RNA-dependent DNA replication

SGD_REF:S000122326
PMID:17429354[8]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006279

premeiotic DNA replication

SGD_REF:S000056892
PMID:2651896[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016779

nucleotidyltransferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0548

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Holmes AM & Haber JE (1999) Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell 96: 415-24 PubMed GONUTS page
  2. 2.0 2.1 2.2 Budd ME et al. (1989) DNA polymerase I is required for premeiotic DNA replication and sporulation but not for X-ray repair in Saccharomyces cerevisiae. Mol Cell Biol 9: 365-76 PubMed GONUTS page
  3. Johnson LM et al. (1985) Isolation of the gene encoding yeast DNA polymerase I. Cell 43: 369-77 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Plevani P et al. (1985) Polypeptide structure of DNA primase from a yeast DNA polymerase-primase complex. J Biol Chem 260: 7102-7 PubMed GONUTS page
  5. Brooke RG et al. (1991) Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. J Biol Chem 266: 3005-15 PubMed GONUTS page
  6. Hiraga S et al. (2005) DNA polymerases alpha, delta, and epsilon localize and function together at replication forks in Saccharomyces cerevisiae. Genes Cells 10: 297-309 PubMed GONUTS page
  7. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  8. Storici F et al. (2007) RNA-templated DNA repair. Nature 447: 338-41 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox