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SGD:PHO23

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) PHO23 ( synonyms: YNL097C )
Protein Name(s) Probable component of the Rpd3 histone deacetylase complex, involved,
External Links
SGD S000005041

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000118

histone deacetylase complex

SGD_REF:S000073630
PMID:12672825[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000069459
PMID:11914276[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001965

F

From SGD

GO:0016479

negative regulation of transcription from RNA polymerase I promoter

SGD_REF:S000129563
PMID:19270272[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016568

chromatin modification

SGD_REF:S000043268
PMID:10805724[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016568

chromatin modification

SGD_REF:S000043268
PMID:10805724[4]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0016568

chromatin modification

SGD_REF:S000043268
PMID:10805724[4]

ISS: Inferred from Sequence or Structural Similarity

P

From SGD

GO:0016568

chromatin modification

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From SGD

GO:0031939

negative regulation of chromatin silencing at telomere

SGD_REF:S000113697
PMID:16314178[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031939

negative regulation of chromatin silencing at telomere

SGD_REF:S000113736
PMID:16286008[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031939

negative regulation of chromatin silencing at telomere

SGD_REF:S000129959
PMID:19372273[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113697
PMID:16314178[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113735
PMID:16286007[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113736
PMID:16286008[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000128493
PMID:19040720[9]

IDA: Inferred from Direct Assay

C

From SGD

GO:0035064

methylated histone residue binding

SGD_REF:S000119974
PMID:17142463[10]

IDA: Inferred from Direct Assay

F

From SGD

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

SGD_REF:S000120303
PMID:17210643[11]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD

GO:0061186

negative regulation of chromatin silencing at silent mating-type cassette

SGD_REF:S000113736
PMID:16286008[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0061188

negative regulation of chromatin silencing at rDNA

SGD_REF:S000113736
PMID:16286008[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0061408

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

SGD_REF:S000133875
PMID:20398213[12]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0070210

Rpd3L-Expanded complex

SGD_REF:S000128493
PMID:19040720[9]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Nourani A et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278: 19171-5 PubMed GONUTS page
  2. Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
  3. Hontz RD et al. (2009) Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Genetics 182: 105-19 PubMed GONUTS page
  4. 4.0 4.1 4.2 Loewith R et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20: 3807-16 PubMed GONUTS page
  5. 5.0 5.1 Carrozza MJ et al. (2005) Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta 1731: 77-87; discussion 75-6 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Keogh MC et al. (2005) Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123: 593-605 PubMed GONUTS page
  7. Zhou J et al. (2009) Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation. Nucleic Acids Res 37: 3699-713 PubMed GONUTS page
  8. Carrozza MJ et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123: 581-92 PubMed GONUTS page
  9. 9.0 9.1 Shevchenko A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9: R167 PubMed GONUTS page
  10. Shi X et al. (2007) Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem 282: 2450-5 PubMed GONUTS page
  11. Sertil O et al. (2007) Direct role for the Rpd3 complex in transcriptional induction of the anaerobic DAN/TIR genes in yeast. Mol Cell Biol 27: 2037-47 PubMed GONUTS page
  12. Ruiz-Roig C et al. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol 76: 1049-62 PubMed GONUTS page
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