![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:PHO23
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | PHO23 ( synonyms: YNL097C ) | |
| Protein Name(s) | Probable component of the Rpd3 histone deacetylase complex, involved, | |
| External Links | ||
| SGD | S000005041 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000118 |
histone deacetylase complex |
SGD_REF:S000073630 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016479 |
negative regulation of transcription from RNA polymerase I promoter |
SGD_REF:S000129563 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000043268 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000043268 |
IPI: Inferred from Physical Interaction |
P |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000043268 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From SGD |
||
| GO:0031939 |
negative regulation of chromatin silencing at telomere |
SGD_REF:S000113697 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031939 |
negative regulation of chromatin silencing at telomere |
SGD_REF:S000113736 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031939 |
negative regulation of chromatin silencing at telomere |
SGD_REF:S000129959 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0033698 |
Rpd3L complex |
SGD_REF:S000113697 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0033698 |
Rpd3L complex |
SGD_REF:S000113735 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0033698 |
Rpd3L complex |
SGD_REF:S000113736 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0033698 |
Rpd3L complex |
SGD_REF:S000128493 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0035064 |
methylated histone residue binding |
SGD_REF:S000119974 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000120303 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0061186 |
negative regulation of chromatin silencing at silent mating-type cassette |
SGD_REF:S000113736 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0061188 |
negative regulation of chromatin silencing at rDNA |
SGD_REF:S000113736 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0061408 |
positive regulation of transcription from RNA polymerase II promoter in response to heat stress |
SGD_REF:S000133875 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0070210 |
Rpd3L-Expanded complex |
SGD_REF:S000128493 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nourani A et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278: 19171-5 PubMed GONUTS page
- ↑ Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
- ↑ Hontz RD et al. (2009) Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Genetics 182: 105-19 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Loewith R et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20: 3807-16 PubMed GONUTS page
- ↑ 5.0 5.1 Carrozza MJ et al. (2005) Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta 1731: 77-87; discussion 75-6 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Keogh MC et al. (2005) Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123: 593-605 PubMed GONUTS page
- ↑ Zhou J et al. (2009) Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation. Nucleic Acids Res 37: 3699-713 PubMed GONUTS page
- ↑ Carrozza MJ et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123: 581-92 PubMed GONUTS page
- ↑ 9.0 9.1 Shevchenko A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9: R167 PubMed GONUTS page
- ↑ Shi X et al. (2007) Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem 282: 2450-5 PubMed GONUTS page
- ↑ Sertil O et al. (2007) Direct role for the Rpd3 complex in transcriptional induction of the anaerobic DAN/TIR genes in yeast. Mol Cell Biol 27: 2037-47 PubMed GONUTS page
- ↑ Ruiz-Roig C et al. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol 76: 1049-62 PubMed GONUTS page