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SGD:OPI1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) OPI1 ( synonyms: YHL020C )
Protein Name(s) Transcriptional regulator of a variety of genes,
External Links
SGD S000001012

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000041557
PMID:1985968[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003714

transcription corepressor activity

SGD_REF:S000061407
PMID:11454208[2]

IPI: Inferred from Physical Interaction

F

From SGD

GO:0005634

nucleus

SGD_REF:S000076332
PMID:15192221[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000122500
PMID:15455074[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005635

nuclear envelope

SGD_REF:S000076332
PMID:15192221[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005654

nucleoplasm

SGD_REF:S000122500
PMID:15455074[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000076332
PMID:15192221[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0095

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0008654

phospholipid biosynthetic process

SGD_REF:S000041557
PMID:1985968[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008654

phospholipid biosynthetic process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0594

P

From SGD

GO:0030968

endoplasmic reticulum unfolded protein response

SGD_REF:S000114750
PMID:16582425[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031965

nuclear membrane

SGD_REF:S000122500
PMID:15455074[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

SGD_REF:S000074120
PMID:12871953[6]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 White MJ et al. (1991) The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper. J Biol Chem 266: 863-72 PubMed GONUTS page
  2. Wagner C et al. (2001) The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2. Mol Microbiol 41: 155-66 PubMed GONUTS page
  3. 3.0 3.1 3.2 Loewen CJ et al. (2004) Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. Science 304: 1644-7 PubMed GONUTS page
  4. 4.0 4.1 4.2 Brickner JH & Walter P (2004) Gene recruitment of the activated INO1 locus to the nuclear membrane. PLoS Biol 2: e342 PubMed GONUTS page
  5. Hancock LC et al. (2006) Genomic analysis of the Opi- phenotype. Genetics 173: 621-34 PubMed GONUTS page
  6. Santiago TC & Mamoun CB (2003) Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p. J Biol Chem 278: 38723-30 PubMed GONUTS page
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