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SGD:NUP2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) NUP2 ( synonyms: YLR335W )
Protein Name(s) Nucleoporin involved in nucleocytoplasmic transport,
External Links
SGD S000004327

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000790

nuclear chromatin

SGD_REF:S000114102
PMID:16365162[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000972

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

SGD_REF:S000138391
PMID:20932479[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000973

posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery

SGD_REF:S000138391
PMID:20932479[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0005198

structural molecule activity

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000058277
PMID:9442897[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR015007

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0906

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0185

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006348

chromatin silencing at telomere

SGD_REF:S000114102
PMID:16365162[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006406

mRNA export from nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006407

rRNA export from nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006408

snRNA export from nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006409

tRNA export from nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006607

NLS-bearing substrate import into nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006607

NLS-bearing substrate import into nucleus

SGD_REF:S000075845
PMID:15039779[6]

IGI: Inferred from Genetic Interaction

SGD:S000000063
SGD:S000001377
SGD:S000002600
SGD:S000005624

P

From SGD

GO:0006608

snRNP protein import into nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006609

mRNA-binding (hnRNP) protein import into nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006610

ribosomal protein import into nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006611

protein export from nucleus

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0006612

protein targeting to membrane

SGD_REF:S000123937
PMID:16929305[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813
UniProtKB-KW:KW-0811

P

From SGD

GO:0006999

nuclear pore organization

SGD_REF:S000058277
PMID:9442897[3]

TAS: Traceable Author Statement

P

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[8]

ISM: Inferred from Sequence Model

C

From SGD

GO:0016973

poly(A)+ mRNA export from nucleus

SGD_REF:S000139600
PMID:21036941[9]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031965

nuclear membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0182

C

From SGD

GO:0031990

mRNA export from nucleus in response to heat stress

SGD_REF:S000125466
PMID:18258809[10]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0046907

intracellular transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000156

P

From SGD

GO:0051028

mRNA transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0509

P

From SGD

GO:0070481

nuclear-transcribed mRNA catabolic process, non-stop decay

SGD_REF:S000123716
PMID:17660569[11]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Dilworth DJ et al. (2005) The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 171: 955-65 PubMed GONUTS page
  2. 2.0 2.1 Light WH et al. (2010) Interaction of a DNA zip code with the nuclear pore complex promotes H2A.Z incorporation and INO1 transcriptional memory. Mol Cell 40: 112-25 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Fabre E & Hurt E (1997) Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking. Annu Rev Genet 31: 277-313 PubMed GONUTS page
  4. Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
  5. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  6. Strawn LA et al. (2004) Minimal nuclear pore complexes define FG repeat domains essential for transport. Nat Cell Biol 6: 197-206 PubMed GONUTS page
  7. King MC et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442: 1003-7 PubMed GONUTS page
  8. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
  9. Powrie EA et al. (2011) A nucleoporin, Nup60p, affects the nuclear and cytoplasmic localization of ASH1 mRNA in S. cerevisiae. RNA 17: 134-44 PubMed GONUTS page
  10. Thomsen R et al. (2008) General, rapid, and transcription-dependent fragmentation of nucleolar antigens in S. cerevisiae mRNA export mutants. RNA 14: 706-16 PubMed GONUTS page
  11. Wilson MA et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177: 773-84 PubMed GONUTS page
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