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SGD:NIC96

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) NIC96 ( synonyms: YFR002W )
Protein Name(s) Component of the nuclear pore complex,
External Links
SGD S000001898

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000055

ribosomal large subunit export from nucleus

SGD_REF:S000059349
PMID:11071906[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0005198

structural molecule activity

SGD_REF:S000136155
PMID:18206968[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000040785
PMID:7688296[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000056415
PMID:10684247[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR007231

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0906

C

From SGD

GO:0005643

nuclear pore

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0185

C

From SGD

GO:0006606

protein import into nucleus

SGD_REF:S000057501
PMID:7828598[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006810

transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR007231

P

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0811
UniProtKB-KW:KW-0813

P

From SGD

GO:0006913

nucleocytoplasmic transport

SGD_REF:S000056415
PMID:10684247[4]

IC: Inferred by Curator

GO:0005643

P

From SGD

GO:0006999

nuclear pore organization

SGD_REF:S000057879
PMID:8682854[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006999

nuclear pore organization

SGD_REF:S000064215
PMID:11121302[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[8]

ISM: Inferred from Sequence Model

C

From SGD

GO:0031965

nuclear membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0182

C

From SGD

GO:0051028

mRNA transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0509

P

From SGD

GO:0055125

Nic96 complex

SGD_REF:S000058025
PMID:9017593[9]

IDA: Inferred from Direct Assay

C

From SGD

GO:0055125

Nic96 complex

SGD_REF:S000086510
PMID:15741174[10]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Stage-Zimmermann T et al. (2000) Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell 11: 3777-89 PubMed GONUTS page
  2. Schrader N et al. (2008) Structural basis of the nic96 subcomplex organization in the nuclear pore channel. Mol Cell 29: 46-55 PubMed GONUTS page
  3. Grandi P et al. (1993) Purification of NSP1 reveals complex formation with 'GLFG' nucleoporins and a novel nuclear pore protein NIC96. EMBO J 12: 3061-71 PubMed GONUTS page
  4. 4.0 4.1 Rout MP et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148: 635-51 PubMed GONUTS page
  5. Grandi P et al. (1995) Functional interaction of Nic96p with a core nucleoporin complex consisting of Nsp1p, Nup49p and a novel protein Nup57p. EMBO J 14: 76-87 PubMed GONUTS page
  6. Zabel U et al. (1996) Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p. J Cell Biol 133: 1141-52 PubMed GONUTS page
  7. Gomez-Ospina N et al. (2000) Yeast nuclear pore complex assembly defects determined by nuclear envelope reconstruction. J Struct Biol 132: 1-5 PubMed GONUTS page
  8. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
  9. Schlaich NL et al. (1997) In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p. Mol Biol Cell 8: 33-46 PubMed GONUTS page
  10. Lutzmann M et al. (2005) Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem 280: 18442-51 PubMed GONUTS page
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