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SGD:MOT2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | MOT2 ( synonyms: YER068W, NOT4, SIG1 ) | |
| Protein Name(s) | Ubiquitin-protein ligase subunit of the CCR4-NOT complex, | |
| External Links | ||
| SGD | S000000870 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0000209 |
protein polyubiquitination |
SGD_REF:S000129902 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0000209 |
protein polyubiquitination |
SGD_REF:S000129902 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0003676 |
nucleic acid binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003723 |
RNA binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From SGD |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000118045 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000129902 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000069437 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016567 |
protein ubiquitination |
SGD_REF:S000118045 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0030015 |
CCR4-NOT core complex |
SGD_REF:S000042122 |
IPI: Inferred from Physical Interaction |
C |
From SGD |
|||
| GO:0031087 |
deadenylation-independent decapping of nuclear-transcribed mRNA |
SGD_REF:S000080830 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
SGD_REF:S000074806 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
SGD_REF:S000145305 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
SGD_REF:S000145305 |
IPI: Inferred from Physical Interaction |
SGD:S000002299 |
P |
From SGD |
||
| GO:0043565 |
sequence-specific DNA binding |
SGD_REF:S000128778 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Mersman DP et al. (2009) Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression. Genes Dev 23: 951-62 PubMed GONUTS page
- ↑ 2.0 2.1 Panasenko O et al. (2006) The yeast Ccr4-Not complex controls ubiquitination of the nascent-associated polypeptide (NAC-EGD) complex. J Biol Chem 281: 31389-98 PubMed GONUTS page
- ↑ Tucker M et al. (2002) Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J 21: 1427-36 PubMed GONUTS page
- ↑ Bai Y et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol Cell Biol 19: 6642-51 PubMed GONUTS page
- ↑ Muhlrad D & Parker R (2005) The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p. EMBO J 24: 1033-45 PubMed GONUTS page
- ↑ Denis CL et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158: 627-34 PubMed GONUTS page
- ↑ 7.0 7.1 Kruk JA et al. (2011) The multifunctional Ccr4-Not complex directly promotes transcription elongation. Genes Dev 25: 581-93 PubMed GONUTS page
- ↑ Badis G et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32: 878-87 PubMed GONUTS page
