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SGD:MMS22

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) MMS22 ( synonyms: YLR320W, SLM2 )
Protein Name(s) Subunit of an E3 ubiquitin ligase complex involved in replication rep,
External Links
SGD S000004312

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000725

recombinational repair

SGD_REF:S000125772
PMID:18321796[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003674

molecular function

SGD_REF:S000069584

ND: No biological Data available

F

From SGD

GO:0005634

nucleus

SGD_REF:S000080900
PMID:15718301[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006281

DNA repair

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From SGD

GO:0006302

double-strand break repair

SGD_REF:S000133286
PMID:20174551[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000133286
PMID:20174551[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From SGD

GO:0031297

replication fork processing

SGD_REF:S000127386
PMID:18704118[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0035361

Cul8-RING ubiquitin ligase complex

SGD_REF:S000133086
PMID:20139071[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0045144

meiotic sister chromatid segregation

SGD_REF:S000124986
PMID:18069899[6]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Duro E et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7: 811-8 PubMed GONUTS page
  2. Baldwin EL et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33: 1021-30 PubMed GONUTS page
  3. 3.0 3.1 Ben-Aroya S et al. (2010) Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair. PLoS Genet 6: e1000852 PubMed GONUTS page
  4. Zaidi IW et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9: 1034-40 PubMed GONUTS page
  5. Mimura S et al. (2010) Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing. J Biol Chem 285: 9858-67 PubMed GONUTS page
  6. Jordan PW et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3: e222 PubMed GONUTS page
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