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SGD:MGM1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) MGM1 ( synonyms: YOR211C, MNA1 )
Protein Name(s) Mitochondrial GTPase,
External Links
SGD S000005737

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000002

mitochondrial genome maintenance

SGD_REF:S000045229
PMID:1532158[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0003924

GTPase activity

SGD_REF:S000059280
PMID:11038181[2]

ISA: Inferred from Sequence Alignment

SGD:S000003924

F

From SGD

GO:0003924

GTPase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001401

F

From SGD

GO:0005525

GTP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001401

F

From SGD

GO:0005525

GTP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0342

F

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

From SGD

GO:0005743

mitochondrial inner membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0999

C

From SGD

GO:0005743

mitochondrial inner membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0168

C

From SGD

GO:0005758

mitochondrial intermembrane space

SGD_REF:S000059280
PMID:11038181[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005758

mitochondrial intermembrane space

SGD_REF:S000073854
PMID:12707284[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006184

GTP catabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001401

P

From SGD

GO:0007005

mitochondrion organization

SGD_REF:S000058923
PMID:15125685[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008053

mitochondrial fusion

SGD_REF:S000072748
PMID:12566426[6]

IDA: Inferred from Direct Assay

P

From SGD

GO:0008053

mitochondrial fusion

SGD_REF:S000073565
PMID:12808034[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008053

mitochondrial fusion

SGD_REF:S000073565
PMID:12808034[7]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0030061

mitochondrial crista

SGD_REF:S000135187
PMID:19505460[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0031304

intrinsic to mitochondrial inner membrane

SGD_REF:S000135187
PMID:19505460[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0031314

extrinsic to mitochondrial inner membrane

SGD_REF:S000059280
PMID:11038181[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0097002

mitochondrial inner boundary membrane

SGD_REF:S000135187
PMID:19505460[8]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Jones BA & Fangman WL (1992) Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin. Genes Dev 6: 380-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Wong ED et al. (2000) The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J Cell Biol 151: 341-52 PubMed GONUTS page
  3. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  4. Herlan M et al. (2003) Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J Biol Chem 278: 27781-8 PubMed GONUTS page
  5. Amutha B et al. (2004) A novel role of Mgm1p, a dynamin-related GTPase, in ATP synthase assembly and cristae formation/maintenance. Biochem J 381: 19-23 PubMed GONUTS page
  6. Wong ED et al. (2003) The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J Cell Biol 160: 303-11 PubMed GONUTS page
  7. 7.0 7.1 Sesaki H et al. (2003) Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane. Mol Biol Cell 14: 2342-56 PubMed GONUTS page
  8. 8.0 8.1 8.2 Zick M et al. (2009) Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion. FEBS Lett 583: 2237-43 PubMed GONUTS page
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