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SGD:MCK1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) MCK1 ( synonyms: YNL307C, CMS1, YPK1 )
Protein Name(s) Protein serine/threonine/tyrosine (dual-specificity) kinase,
External Links
SGD S000005251

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000070

mitotic sister chromatid segregation

SGD_REF:S000050205
PMID:2010084[1]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0000070

mitotic sister chromatid segregation

SGD_REF:S000050205
PMID:2010084[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0004672

protein kinase activity

SGD_REF:S000113918
PMID:16319894[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004672

protein kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002290
InterPro:IPR000719

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000072503
PMID:12529445[3]

ISS: Inferred from Sequence or Structural Similarity

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From SGD

GO:0004712

protein serine/threonine/tyrosine kinase activity

SGD_REF:S000048421
PMID:8407952[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005625

soluble fraction

SGD_REF:S000044085
PMID:1701015[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006303

double-strand break repair via nonhomologous end joining

SGD_REF:S000073203
PMID:12399380[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000048421
PMID:8407952[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000113918
PMID:16319894[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008271
InterPro:IPR002290
InterPro:IPR000719

P

From SGD

GO:0006950

response to stress

SGD_REF:S000072503
PMID:12529445[3]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0006950

response to stress

SGD_REF:S000072503
PMID:12529445[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007126

meiosis

SGD_REF:S000050204
PMID:2010083[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016301

kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From SGD

GO:0016310

phosphorylation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016772

transferase activity, transferring phosphorus-containing groups

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From SGD

GO:0030437

ascospore formation

SGD_REF:S000050204
PMID:2010083[7]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Shero JH & Hieter P (1991) A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1). Genes Dev 5: 549-60 PubMed GONUTS page
  2. 2.0 2.1 Ptacek J et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438: 679-84 PubMed GONUTS page
  3. 3.0 3.1 3.2 Hirata Y et al. (2003) Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes. Mol Biol Cell 14: 302-12 PubMed GONUTS page
  4. 4.0 4.1 Lim MY et al. (1993) Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem 268: 21155-64 PubMed GONUTS page
  5. Dailey D et al. (1990) Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity. Mol Cell Biol 10: 6244-56 PubMed GONUTS page
  6. Wilson TE (2002) A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio. Genetics 162: 677-88 PubMed GONUTS page
  7. 7.0 7.1 Neigeborn L & Mitchell AP (1991) The yeast MCK1 gene encodes a protein kinase homolog that activates early meiotic gene expression. Genes Dev 5: 533-48 PubMed GONUTS page
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