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SGD:LYS2

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) LYS2 ( synonyms: YBR115C )
Protein Name(s) Alpha aminoadipate reductase,
External Links
SGD S000000319

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000036

acyl carrier activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR009081

F

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From SGD

GO:0003824

catalytic activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000873

F

From SGD

GO:0004043

L-aminoadipate-semialdehyde dehydrogenase activity

SGD_REF:S000046365
PMID:10320345[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004043

L-aminoadipate-semialdehyde dehydrogenase activity

SGD_REF:S000054659
PMID:3023949[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004043

L-aminoadipate-semialdehyde dehydrogenase activity

SGD_REF:S000063912
PMID:4401608[3]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004043

L-aminoadipate-semialdehyde dehydrogenase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR010080
InterPro:IPR014397

F

From SGD

GO:0004043

L-aminoadipate-semialdehyde dehydrogenase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:1.2.1.31

F

From SGD

GO:0005737

cytoplasm

SGD_REF:S000039895
PMID:3928261[4]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000074185
PMID:14562095[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0008152

metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000873

P

From SGD

GO:0008652

cellular amino acid biosynthetic process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0028

P

From SGD

GO:0009085

lysine biosynthetic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR014397

P

From SGD

GO:0009085

lysine biosynthetic process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0457

P

From SGD

GO:0016491

oxidoreductase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From SGD

GO:0016874

ligase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR010071

F

From SGD

GO:0019878

lysine biosynthetic process via aminoadipic acid

SGD_REF:S000046365
PMID:10320345[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0019878

lysine biosynthetic process via aminoadipic acid

SGD_REF:S000054659
PMID:3023949[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0019878

lysine biosynthetic process via aminoadipic acid

SGD_REF:S000063912
PMID:4401608[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031177

phosphopantetheine binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006162
InterPro:IPR014397

F

From SGD

GO:0048037

cofactor binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006163

F

From SGD

GO:0055114

oxidation-reduction process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR014397

P

From SGD

GO:0055114

oxidation-reduction process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ehmann DE et al. (1999) Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5. Biochemistry 38: 6171-7 PubMed GONUTS page
  2. 2.0 2.1 Barnes DA & Thorner J (1986) Genetic manipulation of Saccharomyces cerevisiae by use of the LYS2 gene. Mol Cell Biol 6: 2828-38 PubMed GONUTS page
  3. 3.0 3.1 Sinha AK & Bhattacharjee JK (1971) Lysine biosynthesis in Saccharomyces. Conversion of -aminoadipate into -aminoadipic -semialdehyde. Biochem J 125: 743-9 PubMed GONUTS page
  4. Bhattacharjee JK (1985) alpha-Aminoadipate pathway for the biosynthesis of lysine in lower eukaryotes. Crit Rev Microbiol 12: 131-51 PubMed GONUTS page
  5. Huh WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-91 PubMed GONUTS page
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