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SGD:KIN28
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | KIN28 ( synonyms: YDL108W ) | |
| Protein Name(s) | Serine/threonine protein kinase, | |
| External Links | ||
| SGD | S000002266 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000113918 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0723 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0005675 |
holo TFIIH complex |
SGD_REF:S000131946 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006360 |
transcription from RNA polymerase I promoter |
SGD_REF:S000141683 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006366 |
transcription from RNA polymerase II promoter |
SGD_REF:S000046450 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006366 |
transcription from RNA polymerase II promoter |
SGD_REF:S000055122 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006366 |
transcription from RNA polymerase II promoter |
SGD_REF:S000131946 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000113918 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0008353 |
RNA polymerase II carboxy-terminal domain kinase activity |
SGD_REF:S000042904 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0008353 |
RNA polymerase II carboxy-terminal domain kinase activity |
SGD_REF:S000042904 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0008353 |
RNA polymerase II carboxy-terminal domain kinase activity |
SGD_REF:S000046450 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0008353 |
RNA polymerase II carboxy-terminal domain kinase activity |
SGD_REF:S000124037 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016301 |
kinase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From SGD |
||
| GO:0016310 |
phosphorylation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From SGD |
||
| GO:0016740 |
transferase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From SGD |
||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000074499 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000042904 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000042904 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000046450 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000069488 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000131207 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
SGD_REF:S000133098 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0070985 |
TFIIK complex |
SGD_REF:S000069488 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0070985 |
TFIIK complex |
SGD_REF:S000131946 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
|
NOT |
GO:0019912 |
cyclin-dependent protein kinase activating kinase activity |
SGD_REF:S000046450 |
IDA: Inferred from Direct Assay |
F |
From SGD |
||
|
NOT |
GO:0019912 |
cyclin-dependent protein kinase activating kinase activity |
SGD_REF:S000046450 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
||
|
contributes_to |
GO:0000990 |
core RNA polymerase binding transcription factor activity |
SGD_REF:S000131946 |
IC: Inferred by Curator |
GO:0005675 |
F |
From SGD |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ptacek J et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438: 679-84 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Yang C et al. (2010) Improved methods for expression and purification of Saccharomyces cerevisiae TFIIF and TFIIH; identification of a functional Escherichia coli promoter and internal translation initiation within the N-terminal coding region of the TFIIF TFG1 subunit. Protein Expr Purif 70: 172-8 PubMed GONUTS page
- ↑ Iben S et al. (2002) TFIIH plays an essential role in RNA polymerase I transcription. Cell 109: 297-306 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Cismowski MJ et al. (1995) KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Mol Cell Biol 15: 2983-92 PubMed GONUTS page
- ↑ Valay JG et al. (1995) The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J Mol Biol 249: 535-44 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Hengartner CJ et al. (1998) Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol Cell 2: 43-53 PubMed GONUTS page
- ↑ Liu Y et al. (2004) Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex. Mol Cell Biol 24: 1721-35 PubMed GONUTS page
- ↑ 8.0 8.1 Keogh MC et al. (2002) Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation. Mol Cell Biol 22: 1288-97 PubMed GONUTS page
- ↑ Kim M et al. (2009) Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7. J Biol Chem 284: 26421-6 PubMed GONUTS page
- ↑ Akhtar MS et al. (2009) TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. Mol Cell 34: 387-93 PubMed GONUTS page
