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SGD:INP53

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) INP53 ( synonyms: YOR109W, SJL3, SOP2 )
Protein Name(s) Polyphosphatidylinositol phosphatase,
External Links
SGD S000005635

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004438

phosphatidylinositol-3-phosphatase activity

SGD_REF:S000045780
PMID:10224048[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004439

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

SGD_REF:S000045780
PMID:10224048[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004439

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

SGD_REF:S000046224
PMID:9438131[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004439

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.1.3.36

F

From SGD

GO:0005624

membrane fraction

SGD_REF:S000074968
PMID:11598201[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000059158
PMID:11094088[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0006810

transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From SGD

GO:0006897

endocytosis

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0254

P

From SGD

GO:0015031

protein transport

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0030479

actin cortical patch

SGD_REF:S000059158
PMID:11094088[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042578

phosphoric ester hydrolase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002013

F

From SGD

GO:0042598

vesicular fraction

SGD_REF:S000114185
PMID:16406366[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043812

phosphatidylinositol-4-phosphate phosphatase activity

SGD_REF:S000045780
PMID:10224048[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0043813

phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

SGD_REF:S000045780
PMID:10224048[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0046854

phosphatidylinositol phosphorylation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000300

P

From SGD

GO:0046856

phosphatidylinositol dephosphorylation

SGD_REF:S000045780
PMID:10224048[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0046856

phosphatidylinositol dephosphorylation

SGD_REF:S000046224
PMID:9438131[2]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Guo S et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274: 12990-5 PubMed GONUTS page
  2. 2.0 2.1 Srinivasan S et al. (1997) Disruption of three phosphatidylinositol-polyphosphate 5-phosphatase genes from Saccharomyces cerevisiae results in pleiotropic abnormalities of vacuole morphology, cell shape, and osmohomeostasis. Eur J Cell Biol 74: 350-60 PubMed GONUTS page
  3. Ha SA et al. (2001) A novel mechanism for localizing membrane proteins to yeast trans-Golgi network requires function of synaptojanin-like protein. Mol Biol Cell 12: 3175-90 PubMed GONUTS page
  4. 4.0 4.1 Ooms LM et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20: 9376-90 PubMed GONUTS page
  5. Böttcher C et al. (2006) Sjl2p is specifically involved in early steps of endocytosis intimately linked to actin dynamics via the Ark1p/Prk1p kinases. FEBS Lett 580: 633-41 PubMed GONUTS page
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