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SGD:HSF1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) HSF1 ( synonyms: YGL073W, EXA3, MAS3 )
Protein Name(s) Trimeric heat shock transcription factor,
External Links
SGD S000003041

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003700

sequence-specific DNA binding transcription factor activity

SGD_REF:S000043737
PMID:3044612[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003700

sequence-specific DNA binding transcription factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

F

From SGD

GO:0005634

nucleus

SGD_REF:S000073465
PMID:12821147[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0006357

regulation of transcription from RNA polymerase II promoter

SGD_REF:S000043737
PMID:3044612[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006950

response to stress

SGD_REF:S000042518
PMID:8985158[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006950

response to stress

SGD_REF:S000043737
PMID:3044612[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006950

response to stress

SGD_REF:S000045072
PMID:2017170[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006950

response to stress

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0346

P

From SGD

GO:0009408

response to heat

SGD_REF:S000042518
PMID:8985158[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0009408

response to heat

SGD_REF:S000043737
PMID:3044612[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0009408

response to heat

SGD_REF:S000045072
PMID:2017170[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0030474

spindle pole body duplication

SGD_REF:S000070234
PMID:11935220[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0032007

negative regulation of TOR signaling cascade

SGD_REF:S000125523
PMID:18270585[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000232

F

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000128778
PMID:19111667[9]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Wiederrecht G et al. (1988) Isolation of the gene encoding the S. cerevisiae heat shock transcription factor. Cell 54: 841-53 PubMed GONUTS page
  2. Kaida D et al. (2003) Rsp5-Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast. Biochem Biophys Res Commun 306: 1037-41 PubMed GONUTS page
  3. Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
  4. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  5. 5.0 5.1 Nwaka S et al. (1996) The heat shock factor and mitochondrial Hsp70 are necessary for survival of heat shock in Saccharomyces cerevisiae. FEBS Lett 399: 259-63 PubMed GONUTS page
  6. 6.0 6.1 Smith BJ & Yaffe MP (1991) A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and the cell cycle. Mol Cell Biol 11: 2647-55 PubMed GONUTS page
  7. Helfant AH (2002) Composition of the spindle pole body of Saccharomyces cerevisiae and the proteins involved in its duplication. Curr Genet 40: 291-310 PubMed GONUTS page
  8. Bandhakavi S et al. (2008) Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis. PLoS One 3: e1598 PubMed GONUTS page
  9. Badis G et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32: 878-87 PubMed GONUTS page
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