Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

SGD:HRR25

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) HRR25 ( synonyms: YPL204W, KTI14 )
Protein Name(s) Protein kinase involved in regulating diverse events,
External Links
SGD S000006125

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0000775

chromosome, centromeric region

SGD_REF:S000118929
PMID:16990132[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0002098

tRNA wobble uridine modification

SGD_REF:S000127524
PMID:18755837[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0004672

protein kinase activity

SGD_REF:S000113918
PMID:16319894[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004672

protein kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000052192
PMID:1495994[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000118929
PMID:16990132[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR017441
InterPro:IPR000719

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000047008
PMID:8034689[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005654

nucleoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0190

C

From SGD

GO:0005730

nucleolus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0188

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0005816

spindle pole body

SGD_REF:S000122496
PMID:17461799[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000047008
PMID:8034689[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005934

cellular bud tip

SGD_REF:S000074258
PMID:14597664[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005934

cellular bud tip

SGD_REF:S000122496
PMID:17461799[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000074258
PMID:14597664[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000122496
PMID:17461799[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006281

DNA repair

SGD_REF:S000046209
PMID:9012827[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006281

DNA repair

SGD_REF:S000052757
PMID:1887218[9]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006281

DNA repair

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000113918
PMID:16319894[3]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000118929
PMID:16990132[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271

P

From SGD

GO:0006888

ER to Golgi vesicle-mediated transport

SGD_REF:S000044372
PMID:9920934[10]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From SGD

GO:0007067

mitosis

SGD_REF:S000052757
PMID:1887218[9]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016301

kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From SGD

GO:0016310

phosphorylation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016772

transferase activity, transferring phosphorus-containing groups

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From SGD

GO:0033551

monopolin complex

SGD_REF:S000118929
PMID:16990132[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033551

monopolin complex

SGD_REF:S000118929
PMID:16990132[1]

IMP: Inferred from Mutant Phenotype

C

From SGD

GO:0033551

monopolin complex

SGD_REF:S000118929
PMID:16990132[1]

IPI: Inferred from Physical Interaction

SGD:S000000908

C

From SGD

GO:0042274

ribosomal small subunit biogenesis

SGD_REF:S000116235
PMID:16738661[11]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0051455

attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation

SGD_REF:S000118929
PMID:16990132[1]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Petronczki M et al. (2006) Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Cell 126: 1049-64 PubMed GONUTS page
  2. Huang B et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14: 2183-94 PubMed GONUTS page
  3. 3.0 3.1 Ptacek J et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438: 679-84 PubMed GONUTS page
  4. DeMaggio AJ et al. (1992) The budding yeast HRR25 gene product is a casein kinase I isoform. Proc Natl Acad Sci U S A 89: 7008-12 PubMed GONUTS page
  5. 5.0 5.1 Vancura A et al. (1994) A prenylation motif is required for plasma membrane localization and biochemical function of casein kinase I in budding yeast. J Biol Chem 269: 19271-8 PubMed GONUTS page
  6. 6.0 6.1 6.2 Lusk CP et al. (2007) Nup53p is a target of two mitotic kinases, Cdk1p and Hrr25p. Traffic 8: 647-60 PubMed GONUTS page
  7. 7.0 7.1 Kafadar KA et al. (2003) Negative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase I. Genes Dev 17: 2698-708 PubMed GONUTS page
  8. Ho Y et al. (1997) Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94: 581-6 PubMed GONUTS page
  9. 9.0 9.1 Hoekstra MF et al. (1991) HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA. Science 253: 1031-4 PubMed GONUTS page
  10. Murakami A et al. (1999) The inactive form of a yeast casein kinase I suppresses the secretory defect of the sec12 mutant. Implication of negative regulation by the Hrr25 kinase in the vesicle budding from the endoplasmic reticulum. J Biol Chem 274: 3804-10 PubMed GONUTS page
  11. Schäfer T et al. (2006) Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature 441: 651-5 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox