![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:GCD1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | GCD1 ( synonyms: YOR260W, TRA3 ) | |
| Protein Name(s) | Gamma subunit of the translation initiation factor eIF2B, | |
| External Links | ||
| SGD | S000005786 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000054638 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000054638 |
IPI: Inferred from Physical Interaction |
SGD:S000003315 |
F |
From SGD |
||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000066197 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0003743 |
translation initiation factor activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0396 |
F |
From SGD |
||
| GO:0005851 |
eukaryotic translation initiation factor 2B complex |
SGD_REF:S000048815 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006412 |
translation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0648 |
P |
From SGD |
||
| GO:0006413 |
translational initiation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0396 |
P |
From SGD |
||
| GO:0006417 |
regulation of translation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0810 |
P |
From SGD |
||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000039767 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000046065 |
IGI: Inferred from Genetic Interaction |
SGD:S000000735 |
P |
From SGD |
||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000046065 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000048815 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000049826 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006446 |
regulation of translational initiation |
SGD_REF:S000054638 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016740 |
transferase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0032045 |
guanyl-nucleotide exchange factor complex |
SGD_REF:S000048815 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0032045 |
guanyl-nucleotide exchange factor complex |
SGD_REF:S000048920 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0032045 |
guanyl-nucleotide exchange factor complex |
SGD_REF:S000048920 |
IPI: Inferred from Physical Interaction |
SGD:S000002619 |
C |
From SGD |
||
|
contributes_to |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
SGD_REF:S000048815 |
IDA: Inferred from Direct Assay |
F |
From SGD |
||
|
contributes_to |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
SGD_REF:S000048920 |
IDA: Inferred from Direct Assay |
F |
From SGD |
||
|
contributes_to |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
SGD_REF:S000048920 |
IPI: Inferred from Physical Interaction |
SGD:S000002619 |
F |
From SGD |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Cigan AM et al. (1991) Complex formation by positive and negative translational regulators of GCN4. Mol Cell Biol 11: 3217-28 PubMed GONUTS page
- ↑ Ashe MP et al. (2001) A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols. EMBO J 20: 6464-74 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Cigan AM et al. (1993) A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast. Proc Natl Acad Sci U S A 90: 5350-4 PubMed GONUTS page
- ↑ Abastado JP et al. (1991) Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control. Mol Cell Biol 11: 486-96 PubMed GONUTS page
- ↑ 5.0 5.1 Mueller PP & Hinnebusch AG (1986) Multiple upstream AUG codons mediate translational control of GCN4. Cell 45: 201-7 PubMed GONUTS page
- ↑ Hinnebusch AG (1985) A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae. Mol Cell Biol 5: 2349-60 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Pavitt GD et al. (1998) eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev 12: 514-26 PubMed GONUTS page
eg |
rt |
t cont. |