GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
SGD:EXO1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | EXO1 ( synonyms: YOR033C, DHS1 ) | |
| Protein Name(s) | 5'-3' exonuclease and flap-endonuclease involved in recombination, | |
| External Links | ||
| SGD | S000005559 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000706 |
meiotic DNA double-strand break processing |
SGD_REF:S000133105 |
IGI: Inferred from Genetic Interaction |
SGD:S000000981 |
P |
From SGD |
||
| GO:0000723 |
telomere maintenance |
SGD_REF:S000076151 |
IGI: Inferred from Genetic Interaction |
P |
From SGD |
|||
| GO:0000729 |
DNA double-strand break processing |
SGD_REF:S000121300 |
IGI: Inferred from Genetic Interaction |
SGD:S000000184 |
P |
From SGD |
||
| GO:0000729 |
DNA double-strand break processing |
SGD_REF:S000121300 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From SGD |
||
| GO:0003824 |
catalytic activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004518 |
nuclease activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004518 |
nuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0540 |
F |
From SGD |
||
| GO:0004527 |
exonuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0269 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000061193 |
IPI: Inferred from Physical Interaction |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0006281 |
DNA repair |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From SGD |
||
| GO:0006298 |
mismatch repair |
SGD_REF:S000061193 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006974 |
response to DNA damage stimulus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From SGD |
||
| GO:0008409 |
5'-3' exonuclease activity |
SGD_REF:S000072317 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0016788 |
hydrolase activity, acting on ester bonds |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0017108 |
5'-flap endonuclease activity |
SGD_REF:S000072317 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0031292 |
gene conversion at mating-type locus, DNA double-strand break processing |
SGD_REF:S000127883 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031860 |
telomeric 3' overhang formation |
SGD_REF:S000136197 |
IGI: Inferred from Genetic Interaction |
SGD:S000002379 |
P |
From SGD |
||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Manfrini N et al. (2010) Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases. J Biol Chem 285: 11628-37 PubMed GONUTS page
- ↑ Bertuch AA & Lundblad V (2004) EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae. Genetics 166: 1651-9 PubMed GONUTS page
- ↑ 3.0 3.1 Mantiero D et al. (2007) Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. EMBO Rep 8: 380-7 PubMed GONUTS page
- ↑ 4.0 4.1 Amin NS et al. (2001) exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol 21: 5142-55 PubMed GONUTS page
- ↑ 5.0 5.1 Tran PT et al. (2002) Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae. DNA Repair (Amst) 1: 895-912 PubMed GONUTS page
- ↑ Mimitou EP & Symington LS (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455: 770-4 PubMed GONUTS page
- ↑ Ngo HP & Lydall D (2010) Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9. PLoS Genet 6: e1001072 PubMed GONUTS page
5cde |
ghm
n |
n cont.rt |
