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SGD:ESA1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | ESA1 ( synonyms: YOR244W, TAS1 ) | |
| Protein Name(s) | Catalytic subunit of the histone acetyltransferase complex NuA4, | |
| External Links | ||
| SGD | S000005770 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000183 |
chromatin silencing at rDNA |
SGD_REF:S000120548 |
IGI: Inferred from Genetic Interaction |
SGD:S000002200 |
P |
From SGD |
||
| GO:0000183 |
chromatin silencing at rDNA |
SGD_REF:S000120548 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0004402 |
histone acetyltransferase activity |
SGD_REF:S000051286 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0004402 |
histone acetyltransferase activity |
SGD_REF:S000124037 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000071516 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006281 |
DNA repair |
SGD_REF:S000114730 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006354 |
transcription elongation, DNA-dependent |
SGD_REF:S000082344 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006354 |
transcription elongation, DNA-dependent |
SGD_REF:S000082344 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000060726 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0010485 |
H4 histone acetyltransferase activity |
SGD_REF:S000071525 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From SGD |
||
| GO:0016573 |
histone acetylation |
SGD_REF:S000051286 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0016573 |
histone acetylation |
SGD_REF:S000054358 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0016573 |
histone acetylation |
SGD_REF:S000124037 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0016740 |
transferase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From SGD |
||
| GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0032777 |
Piccolo NuA4 histone acetyltransferase complex |
SGD_REF:S000073623 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
SGD_REF:S000131988 |
IGI: Inferred from Genetic Interaction |
SGD:S000003484 |
P |
From SGD |
||
| GO:0032968 |
positive regulation of transcription elongation from RNA polymerase II promoter |
SGD_REF:S000131988 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0034401 |
regulation of transcription by chromatin organization |
SGD_REF:S000069392 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0035267 |
NuA4 histone acetyltransferase complex |
SGD_REF:S000051286 |
IPI: Inferred from Physical Interaction |
C |
From SGD |
|||
| GO:0035267 |
NuA4 histone acetyltransferase complex |
SGD_REF:S000079775 |
IPI: Inferred from Physical Interaction |
C |
From SGD |
|||
| GO:0051726 |
regulation of cell cycle |
SGD_REF:S000054358 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Clarke AS et al. (2006) Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. Mol Biol Cell 17: 1744-57 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Allard S et al. (1999) NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J 18: 5108-19 PubMed GONUTS page
- ↑ Bird AW et al. (2002) Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. Nature 419: 411-5 PubMed GONUTS page
- ↑ Utley RT et al. (2005) Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. Mol Cell Biol 25: 8179-90 PubMed GONUTS page
- ↑ 5.0 5.1 Morillon A et al. (2005) Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription. Mol Cell 18: 723-34 PubMed GONUTS page
- ↑ Eisen A et al. (2001) The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation. J Biol Chem 276: 3484-91 PubMed GONUTS page
- ↑ Adachi N et al. (2002) A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3. J Biol Chem 277: 35688-95 PubMed GONUTS page
- ↑ 8.0 8.1 Clarke AS et al. (1999) Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol Cell Biol 19: 2515-26 PubMed GONUTS page
- ↑ Boudreault AA et al. (2003) Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin. Genes Dev 17: 1415-28 PubMed GONUTS page
- ↑ 10.0 10.1 Ginsburg DS et al. (2009) NuA4 lysine acetyltransferase Esa1 is targeted to coding regions and stimulates transcription elongation with Gcn5. Mol Cell Biol 29: 6473-87 PubMed GONUTS page
- ↑ Verdone L et al. (2002) Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions. EMBO J 21: 1101-11 PubMed GONUTS page
- ↑ Zhang H et al. (2004) The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Mol Cell Biol 24: 9424-36 PubMed GONUTS page
