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SGD:DUO1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) DUO1 ( synonyms: YGL061C )
Protein Name(s) Essential subunit of the Dam1 complex (aka DASH complex),
External Links
SGD S000003029

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000775

chromosome, centromeric region

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0137

C

From SGD

GO:0000776

kinetochore

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0995

C

From SGD

GO:0000777

condensed chromosome kinetochore

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0149

C

From SGD

GO:0000778

condensed nuclear chromosome kinetochore

SGD_REF:S000069091
PMID:11756468[1]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0005200

structural constituent of cytoskeleton

SGD_REF:S000069091
PMID:11756468[1]

IPI: Inferred from Physical Interaction

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005694

chromosome

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0158

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005816

spindle pole body

SGD_REF:S000046073
PMID:9817759[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005819

spindle

SGD_REF:S000069091
PMID:11756468[1]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0005819

spindle

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0251

C

From SGD

GO:0005856

cytoskeleton

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From SGD

GO:0005874

microtubule

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0493

C

From SGD

GO:0005876

spindle microtubule

SGD_REF:S000046073
PMID:9817759[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0007059

chromosome segregation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0159

P

From SGD

GO:0007067

mitosis

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0498

P

From SGD

GO:0030472

mitotic spindle organization in nucleus

SGD_REF:S000069091
PMID:11756468[1]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[3]

IDA: Inferred from Direct Assay

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[3]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[4]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[5]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[3]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0051301

cell division

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From SGD

contributes_to

GO:0008017

microtubule binding

SGD_REF:S000116677
PMID:16777964[6]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Cheeseman IM et al. (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155: 1137-45 PubMed GONUTS page
  2. 2.0 2.1 Hofmann C et al. (1998) Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function. J Cell Biol 143: 1029-40 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Westermann S et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17: 277-90 PubMed GONUTS page
  4. 4.0 4.1 Li Y et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16: 183-97 PubMed GONUTS page
  5. 5.0 5.1 Miranda JJ et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12: 138-43 PubMed GONUTS page
  6. Asbury CL et al. (2006) The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement. Proc Natl Acad Sci U S A 103: 9873-8 PubMed GONUTS page
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