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SGD:DPB11
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | DPB11 ( synonyms: YJL090C ) | |
| Protein Name(s) | Replication initiation protein that loads DNA pol epsilon, | |
| External Links | ||
| SGD | S000003626 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000076 |
DNA replication checkpoint |
SGD_REF:S000046281 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000725 |
recombinational repair |
SGD_REF:S000117068 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0000725 |
recombinational repair |
SGD_REF:S000117068 |
IGI: Inferred from Genetic Interaction |
SGD:S000004494 |
P |
From SGD |
||
| GO:0000727 |
double-strand break repair via break-induced replication |
SGD_REF:S000134596 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
SGD_REF:S000128000 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
SGD_REF:S000128012 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0005515 |
protein binding |
SGD_REF:S000043352 |
IPI: Inferred from Physical Interaction |
SGD:S000005206 |
F |
From SGD |
||
| GO:0005622 |
intracellular |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0005657 |
replication fork |
SGD_REF:S000043352 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005657 |
replication fork |
SGD_REF:S000058372 |
TAS: Traceable Author Statement |
C |
From SGD |
|||
| GO:0006260 |
DNA replication |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0235 |
P |
From SGD |
||
| GO:0006270 |
DNA-dependent DNA replication initiation |
SGD_REF:S000073092 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0006272 |
leading strand elongation |
SGD_REF:S000058372 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0006273 |
lagging strand elongation |
SGD_REF:S000058372 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0006289 |
nucleotide-excision repair |
SGD_REF:S000058372 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0006298 |
mismatch repair |
SGD_REF:S000058456 |
NAS: Non-traceable Author Statement |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
SGD_REF:S000126696 |
IGI: Inferred from Genetic Interaction |
SGD:S000002848 |
P |
From SGD |
||
| GO:0007533 |
mating type switching |
SGD_REF:S000141705 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0030295 |
protein kinase activator activity |
SGD_REF:S000128012 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0031261 |
DNA replication preinitiation complex |
SGD_REF:S000120052 |
IMP: Inferred from Mutant Phenotype |
C |
From SGD |
|||
|
colocalizes_with |
GO:0008622 |
epsilon DNA polymerase complex |
SGD_REF:S000043352 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wang H & Elledge SJ (1999) DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96: 3824-9 PubMed GONUTS page
- ↑ 2.0 2.1 Ogiwara H et al. (2006) Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res 34: 3389-98 PubMed GONUTS page
- ↑ Lydeard JR et al. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev 24: 1133-44 PubMed GONUTS page
- ↑ Nunez LR et al. (2008) Cell wall integrity MAPK pathway is essential for lipid homeostasis. J Biol Chem 283: 34204-17 PubMed GONUTS page
- ↑ 5.0 5.1 Navadgi-Patil VM & Burgers PM (2008) Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase. J Biol Chem 283: 35853-9 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Masumoto H et al. (2000) Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol Cell Biol 20: 2809-17 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Burgers PM (1998) Eukaryotic DNA polymerases in DNA replication and DNA repair. Chromosoma 107: 218-27 PubMed GONUTS page
- ↑ Takayama Y et al. (2003) GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev 17: 1153-65 PubMed GONUTS page
- ↑ Kolodner RD & Marsischky GT (1999) Eukaryotic DNA mismatch repair. Curr Opin Genet Dev 9: 89-96 PubMed GONUTS page
- ↑ Puddu F et al. (2008) Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint. Mol Cell Biol 28: 4782-93 PubMed GONUTS page
- ↑ Germann SM et al. (2011) Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination. DNA Repair (Amst) 10: 210-24 PubMed GONUTS page
- ↑ Tanaka S et al. (2007) CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast. Nature 445: 328-32 PubMed GONUTS page
