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SGD:DOM34
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | DOM34 ( synonyms: YNL001W ) | |
| Protein Name(s) | Protein involved in ribosomal dissociation when translation is stalled, | |
| External Links | ||
| SGD | S000004946 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000294 |
nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay |
SGD_REF:S000124263 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0004518 |
nuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0540 |
F |
From SGD |
||
| GO:0004519 |
endonuclease activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0255 |
F |
From SGD |
||
| GO:0004521 |
endoribonuclease activity |
SGD_REF:S000124263 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000074185 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From SGD |
||
| GO:0005737 |
cytoplasm |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0086 |
C |
From SGD |
||
| GO:0006412 |
translation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0648 |
P |
From SGD |
||
| GO:0006417 |
regulation of translation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0810 |
P |
From SGD |
||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0007067 |
mitosis |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0498 |
P |
From SGD |
||
| GO:0007126 |
meiosis |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0469 |
P |
From SGD |
||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From SGD |
||
| GO:0032790 |
ribosome disassembly |
SGD_REF:S000140925 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
||
| GO:0070651 |
nonfunctional rRNA decay |
SGD_REF:S000130555 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0070966 |
nuclear-transcribed mRNA catabolic process, no-go decay |
SGD_REF:S000114969 |
IGI: Inferred from Genetic Interaction |
SGD:S000005602 |
P |
From SGD |
||
| GO:0070966 |
nuclear-transcribed mRNA catabolic process, no-go decay |
SGD_REF:S000130237 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
|
NOT |
GO:0004521 |
endoribonuclease activity |
SGD_REF:S000130237 |
IDA: Inferred from Direct Assay |
F |
From SGD |
||
|
contributes_to |
GO:0043022 |
ribosome binding |
SGD_REF:S000145838 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lee HH et al. (2007) Structural and functional insights into Dom34, a key component of no-go mRNA decay. Mol Cell 27: 938-50 PubMed GONUTS page
- ↑ Huh WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-91 PubMed GONUTS page
- ↑ Shoemaker CJ et al. (2010) Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science 330: 369-72 PubMed GONUTS page
- ↑ Cole SE et al. (2009) A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay. Mol Cell 34: 440-50 PubMed GONUTS page
- ↑ Doma MK & Parker R (2006) Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature 440: 561-4 PubMed GONUTS page
- ↑ 6.0 6.1 Passos DO et al. (2009) Analysis of Dom34 and its function in no-go decay. Mol Biol Cell 20: 3025-32 PubMed GONUTS page
- ↑ Becker T et al. (2011) Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome. Nat Struct Mol Biol 18: 715-20 PubMed GONUTS page
