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SGD:DNF1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) DNF1 ( synonyms: YER166W )
Protein Name(s) Plasma membrane aminophospholipid translocase (flippase),
External Links
SGD S000000968

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008250

F

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

From SGD

GO:0000287

magnesium ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006539

F

From SGD

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000075362
PMID:12631737[1]

IGI: Inferred from Genetic Interaction

SGD:S000002500

F

From SGD

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000119111
PMID:17015438[2]

IGI: Inferred from Genetic Interaction

SGD:S000002500

F

From SGD

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000119111
PMID:17015438[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006539

F

From SGD

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.6.3.1

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006539
InterPro:IPR001757
InterPro:IPR018303

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005768

endosome

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0967

C

From SGD

GO:0005794

Golgi apparatus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0333

C

From SGD

GO:0005794

Golgi apparatus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0132

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000071441
PMID:12221123[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000075362
PMID:12631737[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

From SGD

GO:0006810

transport

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

From SGD

GO:0006812

cation transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001757

P

From SGD

GO:0006869

lipid transport

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0445

P

From SGD

GO:0006886

intracellular protein transport

SGD_REF:S000071441
PMID:12221123[5]

IGI: Inferred from Genetic Interaction

SGD:S000002500
SGD:S000000024
SGD:S000004772

P

From SGD

GO:0006897

endocytosis

SGD_REF:S000075362
PMID:12631737[1]

IGI: Inferred from Genetic Interaction

SGD:S000000024
SGD:S000002500

P

From SGD

GO:0006897

endocytosis

SGD_REF:S000075362
PMID:12631737[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007163

establishment or maintenance of cell polarity

SGD_REF:S000077553
PMID:15461661[6]

IGI: Inferred from Genetic Interaction

SGD:S000002500

P

From SGD

GO:0010008

endosome membrane

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0100

C

From SGD

GO:0015662

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

SGD_REF:S000119132
PMID:9224683[7]

ISS: Inferred from Sequence or Structural Similarity

SGD:S000003135
SGD:S000002447

F

From SGD

GO:0015662

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001757

F

From SGD

GO:0015914

phospholipid transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006539

P

From SGD

GO:0016020

membrane

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001757

C

From SGD

GO:0016020

membrane

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[8]

ISM: Inferred from Sequence Model

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR006539

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

From SGD

GO:0016820

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR023306

F

From SGD

GO:0045332

phospholipid translocation

SGD_REF:S000075362
PMID:12631737[1]

IGI: Inferred from Genetic Interaction

SGD:S000002500

P

From SGD

GO:0045332

phospholipid translocation

SGD_REF:S000119111
PMID:17015438[2]

IGI: Inferred from Genetic Interaction

SGD:S000002500

P

From SGD

GO:0045332

phospholipid translocation

SGD_REF:S000119111
PMID:17015438[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0046872

metal ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008250

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Pomorski T et al. (2003) Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol Biol Cell 14: 1240-54 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Riekhof WR & Voelker DR (2006) Uptake and utilization of lyso-phosphatidylethanolamine by Saccharomyces cerevisiae. J Biol Chem 281: 36588-96 PubMed GONUTS page
  3. Sickmann A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100: 13207-12 PubMed GONUTS page
  4. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  5. 5.0 5.1 Hua Z et al. (2002) An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system. Mol Biol Cell 13: 3162-77 PubMed GONUTS page
  6. Iwamoto K et al. (2004) Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity. Genes Cells 9: 891-903 PubMed GONUTS page
  7. Catty P et al. (1997) The complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases. FEBS Lett 409: 325-32 PubMed GONUTS page
  8. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
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