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SGD:DMC1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) DMC1 ( synonyms: YER179W, ISC2 )
Protein Name(s) Meiosis-specific protein involved in DSB repair and chromosome pairing,
External Links
SGD S000000981

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR003593
InterPro:IPR010995

F

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

From SGD

GO:0000709

meiotic joint molecule formation

SGD_REF:S000046433
PMID:9323140[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000794

condensed nuclear chromosome

SGD_REF:S000047546
PMID:1581960[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020587
InterPro:IPR020588

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

From SGD

GO:0003690

double-stranded DNA binding

SGD_REF:S000066194
PMID:11551925[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003697

single-stranded DNA binding

SGD_REF:S000066194
PMID:11551925[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020587
InterPro:IPR020588

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000049325
PMID:7528104[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011940

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

From SGD

GO:0006259

DNA metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR020587
InterPro:IPR020588

P

From SGD

GO:0007049

cell cycle

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

From SGD

GO:0007126

meiosis

SGD_REF:S000047546
PMID:1581960[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007126

meiosis

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0469

P

From SGD

GO:0007131

reciprocal meiotic recombination

SGD_REF:S000047546
PMID:1581960[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007131

reciprocal meiotic recombination

SGD_REF:S000114778
PMID:16581767[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007131

reciprocal meiotic recombination

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011940

P

From SGD

GO:0008094

DNA-dependent ATPase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011940
InterPro:IPR020587
InterPro:IPR020588

F

From SGD

GO:0017111

nucleoside-triphosphatase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

From SGD

GO:0030435

sporulation resulting in formation of a cellular spore

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0749

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Schwacha A & Kleckner N (1997) Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell 90: 1123-35 PubMed GONUTS page
  2. 2.0 2.1 2.2 Bishop DK et al. (1992) DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69: 439-56 PubMed GONUTS page
  3. 3.0 3.1 Hong EL et al. (2001) Saccharomyces cerevisiae Dmc1 protein promotes renaturation of single-strand DNA (ssDNA) and assimilation of ssDNA into homologous super-coiled duplex DNA. J Biol Chem 276: 41906-12 PubMed GONUTS page
  4. Bishop DK (1994) RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell 79: 1081-92 PubMed GONUTS page
  5. Henry JM et al. (2006) Mnd1/Hop2 facilitates Dmc1-dependent interhomolog crossover formation in meiosis of budding yeast. Mol Cell Biol 26: 2913-23 PubMed GONUTS page
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