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SGD:CYC8

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CYC8 ( synonyms: YBR112C, CRT8, SSN6, (OCT1+), (OCT) )
Protein Name(s) General transcriptional co-repressor,
External Links
SGD S000000316

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003713

transcription coactivator activity

SGD_REF:S000062263
PMID:9867831[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003713

transcription coactivator activity

SGD_REF:S000062263
PMID:9867831[1]

IGI: Inferred from Genetic Interaction

F

From SGD

GO:0003713

transcription coactivator activity

SGD_REF:S000062263
PMID:9867831[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0003713

transcription coactivator activity

SGD_REF:S000062263
PMID:9867831[1]

IPI: Inferred from Physical Interaction

F

From SGD

GO:0005488

binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011990

F

From SGD

GO:0005634

nucleus

SGD_REF:S000055359
PMID:1739976[2]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

From SGD

GO:0006338

chromatin remodeling

SGD_REF:S000076895
PMID:14739928[3]

IGI: Inferred from Genetic Interaction

SGD:S000006256
SGD:S000002157

P

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

From SGD

GO:0016584

nucleosome positioning

SGD_REF:S000076511
PMID:15116071[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0017053

transcriptional repressor complex

SGD_REF:S000045412
PMID:9111019[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0035955

negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000127448
PMID:18708352[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0045892

negative regulation of transcription, DNA-dependent

SGD_REF:S000055359
PMID:1739976[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0045892

negative regulation of transcription, DNA-dependent

SGD_REF:S000055359
PMID:1739976[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0045892

negative regulation of transcription, DNA-dependent

SGD_REF:S000055359
PMID:1739976[2]

IPI: Inferred from Physical Interaction

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Conlan RS et al. (1999) The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator. J Biol Chem 274: 205-10 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Keleher CA et al. (1992) Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68: 709-19 PubMed GONUTS page
  3. Fragiadakis GS et al. (2004) Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation. EMBO J 23: 333-42 PubMed GONUTS page
  4. Zhang Z & Reese JC (2004) Ssn6-Tup1 requires the ISW2 complex to position nucleosomes in Saccharomyces cerevisiae. EMBO J 23: 2246-57 PubMed GONUTS page
  5. Redd MJ et al. (1997) A complex composed of tup1 and ssn6 represses transcription in vitro. J Biol Chem 272: 11193-7 PubMed GONUTS page
  6. Xia Z et al. (2008) Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter. J Biol Chem 283: 28958-68 PubMed GONUTS page
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