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SGD:CUP5

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) VMA3 ( synonyms: YEL027W, CLS7, CUP5, GEF2 )
Protein Name(s) Proteolipid subunit c of the V0 domain of V-ATPase,
External Links
SGD S000000753

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000220

vacuolar proton-transporting V-type ATPase, V0 domain

SGD_REF:S000056362
PMID:10224039[1]

TAS: Traceable Author Statement

C

From SGD

GO:0000220

vacuolar proton-transporting V-type ATPase, V0 domain

SGD_REF:S000058276
PMID:9442887[2]

TAS: Traceable Author Statement

C

From SGD

GO:0005773

vacuole

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0926

C

From SGD

GO:0005774

vacuolar membrane

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0271

C

From SGD

GO:0006623

protein targeting to vacuole

SGD_REF:S000040485
PMID:2145283[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006810

transport

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

From SGD

GO:0006811

ion transport

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

From SGD

GO:0006878

cellular copper ion homeostasis

SGD_REF:S000040756
PMID:9434348[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006879

cellular iron ion homeostasis

SGD_REF:S000040756
PMID:9434348[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006897

endocytosis

SGD_REF:S000040485
PMID:2145283[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007033

vacuole organization

SGD_REF:S000040485
PMID:2145283[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007035

vacuolar acidification

SGD_REF:S000056362
PMID:10224039[1]

TAS: Traceable Author Statement

P

From SGD

GO:0007035

vacuolar acidification

SGD_REF:S000058276
PMID:9442887[2]

TAS: Traceable Author Statement

P

From SGD

GO:0015078

hydrogen ion transmembrane transporter activity

SGD_REF:S000073046
PMID:12482875[5]

TAS: Traceable Author Statement

F

From SGD

GO:0015078

hydrogen ion transmembrane transporter activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011555
InterPro:IPR002379
InterPro:IPR000245

F

From SGD

GO:0015991

ATP hydrolysis coupled proton transport

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011555
InterPro:IPR002379
InterPro:IPR000245

P

From SGD

GO:0015992

proton transport

SGD_REF:S000073046
PMID:12482875[5]

TAS: Traceable Author Statement

P

From SGD

GO:0015992

proton transport

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0375

P

From SGD

GO:0016020

membrane

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000077169
PMID:15252052[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[7]

ISM: Inferred from Sequence Model

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

From SGD

GO:0033177

proton-transporting two-sector ATPase complex, proton-transporting domain

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002379

C

From SGD

GO:0033179

proton-transporting V-type ATPase, V0 domain

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000245
InterPro:IPR011555

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Forgac M (1999) Structure and properties of the vacuolar (H+)-ATPases. J Biol Chem 274: 12951-4 PubMed GONUTS page
  2. 2.0 2.1 Stevens TH & Forgac M (1997) Structure, function and regulation of the vacuolar (H+)-ATPase. Annu Rev Cell Dev Biol 13: 779-808 PubMed GONUTS page
  3. 3.0 3.1 3.2 Umemoto N et al. (1990) Roles of the VMA3 gene product, subunit c of the vacuolar membrane H(+)-ATPase on vacuolar acidification and protein transport. A study with VMA3-disrupted mutants of Saccharomyces cerevisiae. J Biol Chem 265: 18447-53 PubMed GONUTS page
  4. 4.0 4.1 Szczypka MS et al. (1997) Saccharomyces cerevisiae mutants altered in vacuole function are defective in copper detoxification and iron-responsive gene transcription. Yeast 13: 1423-35 PubMed GONUTS page
  5. 5.0 5.1 Nishi T et al. (2003) The first putative transmembrane segment of subunit c" (Vma16p) of the yeast V-ATPase is not necessary for function. J Biol Chem 278: 5821-7 PubMed GONUTS page
  6. Flannery AR et al. (2004) Topological characterization of the c, c', and c" subunits of the vacuolar ATPase from the yeast Saccharomyces cerevisiae. J Biol Chem 279: 39856-62 PubMed GONUTS page
  7. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
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