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SGD:CSE4

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CSE4 ( synonyms: YKL049C, CSL2 )
Protein Name(s) Centromere protein that resembles histone H3,
External Links
SGD S000001532

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000070

mitotic sister chromatid segregation

SGD_REF:S000046262
PMID:7698647[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000775

chromosome, centromeric region

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0137

C

From SGD

GO:0000776

kinetochore

SGD_REF:S000052739
PMID:10958698[2]

IGI: Inferred from Genetic Interaction

C

From SGD

GO:0000776

kinetochore

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0995

C

From SGD

GO:0000777

condensed chromosome kinetochore

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0149

C

From SGD

GO:0000780

condensed nuclear chromosome, centromeric region

SGD_REF:S000059419
PMID:11063678[3]

IGI: Inferred from Genetic Interaction

C

From SGD

GO:0000786

nucleosome

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000164

C

From SGD

GO:0000788

nuclear nucleosome

SGD_REF:S000059419
PMID:11063678[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR009072
InterPro:IPR007125
InterPro:IPR000164

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

From SGD

GO:0005634

nucleus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

From SGD

GO:0005694

chromosome

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0158

C

From SGD

GO:0005727

extrachromosomal circular DNA

SGD_REF:S000118838
PMID:16966420[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006334

nucleosome assembly

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000164

P

From SGD

GO:0019237

centromeric DNA binding

SGD_REF:S000059419
PMID:11063678[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0030543

2-micrometer plasmid partitioning

SGD_REF:S000118838
PMID:16966420[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043505

centromere-specific nucleosome

SGD_REF:S000133097
PMID:19782029[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000118838
PMID:16966420[4]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Stoler S et al. (1995) A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes Dev 9: 573-86 PubMed GONUTS page
  2. Chen Y et al. (2000) The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain. Mol Cell Biol 20: 7037-48 PubMed GONUTS page
  3. 3.0 3.1 3.2 Keith KC & Fitzgerald-Hayes M (2000) CSE4 genetically interacts with the Saccharomyces cerevisiae centromere DNA elements CDE I and CDE II but not CDE III. Implications for the path of the centromere dna around a cse4p variant nucleosome. Genetics 156: 973-81 PubMed GONUTS page
  4. 4.0 4.1 4.2 Hajra S et al. (2006) The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation. J Cell Biol 174: 779-90 PubMed GONUTS page
  5. Camahort R et al. (2009) Cse4 is part of an octameric nucleosome in budding yeast. Mol Cell 35: 794-805 PubMed GONUTS page
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