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SGD:COX4

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) COX4 ( synonyms: YGL187C )
Protein Name(s) Subunit IV of cytochrome c oxidase,
External Links
SGD S000003155

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0033617

mitochondrial respiratory chain complex IV assembly

PMID:22342701[1]

IMP: Inferred from Mutant Phenotype

P

Figure 2 (B). The lack of band in lane 14 and 16 compared to the WT bands at the specific high molecular weight of 230 and 440 kDa indicates the lack of complex IV in mutant cox4.

complete

GO:0004129

cytochrome-c oxidase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002124

F

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

From SGD

GO:0005740

mitochondrial envelope

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002124

C

From SGD

GO:0005743

mitochondrial inner membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0999

C

From SGD

GO:0005743

mitochondrial inner membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0168

C

From SGD

GO:0005751

mitochondrial respiratory chain complex IV

SGD_REF:S000056478
PMID:1331058[3]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0006123

mitochondrial electron transport, cytochrome c to oxygen

SGD_REF:S000056478
PMID:1331058[3]

IDA: Inferred from Direct Assay

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000120343
PMID:17215247[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0009060

aerobic respiration

SGD_REF:S000062372
PMID:163235[5]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[6]

ISM: Inferred from Sequence Model

C

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD

contributes_to

GO:0004129

cytochrome-c oxidase activity

SGD_REF:S000056478
PMID:1331058[3]

IPI: Inferred from Physical Interaction

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Vukotic M et al. (2012) Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metab 15: 336-47 PubMed GONUTS page
  2. Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
  3. 3.0 3.1 3.2 Taanman JW & Capaldi RA (1992) Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J Biol Chem 267: 22481-5 PubMed GONUTS page
  4. Coyne HJ 3rd et al. (2007) The characterization and role of zinc binding in yeast Cox4. J Biol Chem 282: 8926-34 PubMed GONUTS page
  5. Eytan GD & Schatz G (1975) Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J Biol Chem 250: 767-74 PubMed GONUTS page
  6. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
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