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SGD:CDC6
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | CDC6 ( synonyms: YJL194W ) | |
| Protein Name(s) | Essential ATP-binding protein required for DNA replication, | |
| External Links | ||
| SGD | S000003730 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000082 |
G1/S transition of mitotic cell cycle |
SGD_REF:S000039113 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0003682 |
chromatin binding |
SGD_REF:S000039113 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0003682 |
chromatin binding |
SGD_REF:S000055375 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003682 |
chromatin binding |
SGD_REF:S000055436 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003688 |
DNA replication origin binding |
SGD_REF:S000055375 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003688 |
DNA replication origin binding |
SGD_REF:S000117043 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003924 |
GTPase activity |
SGD_REF:S000042228 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005515 |
protein binding |
SGD_REF:S000039113 |
IPI: Inferred from Physical Interaction |
SGD:S000004530 |
F |
From SGD |
||
| GO:0005515 |
protein binding |
SGD_REF:S000040889 |
IPI: Inferred from Physical Interaction |
SGD:S000001885 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000039113 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000042228 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005525 |
GTP binding |
SGD_REF:S000042228 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005656 |
pre-replicative complex |
SGD_REF:S000117043 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005886 |
plasma membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From SGD |
||
| GO:0005886 |
plasma membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0039 |
C |
From SGD |
||
| GO:0006260 |
DNA replication |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0235 |
P |
From SGD |
||
| GO:0006267 |
pre-replicative complex assembly |
SGD_REF:S000039113 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006267 |
pre-replicative complex assembly |
SGD_REF:S000047121 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006267 |
pre-replicative complex assembly |
SGD_REF:S000054350 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006267 |
pre-replicative complex assembly |
SGD_REF:S000117043 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016887 |
ATPase activity |
SGD_REF:S000042228 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0017111 |
nucleoside-triphosphatase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0030174 |
regulation of DNA-dependent DNA replication initiation |
SGD_REF:S000047962 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031261 |
DNA replication preinitiation complex |
SGD_REF:S000055792 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0031938 |
regulation of chromatin silencing at telomere |
SGD_REF:S000118920 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Wang B et al. (1999) The essential role of Saccharomyces cerevisiae CDC6 nucleotide-binding site in cell growth, DNA synthesis, and Orc1 association. J Biol Chem 274: 8291-8 PubMed GONUTS page
- ↑ 2.0 2.1 Tanaka T et al. (1997) Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell 90: 649-60 PubMed GONUTS page
- ↑ Donovan S et al. (1997) Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. Proc Natl Acad Sci U S A 94: 5611-6 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Kawasaki Y et al. (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11: 745-56 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Zwerschke W et al. (1994) The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation. J Biol Chem 269: 23351-6 PubMed GONUTS page
- ↑ Drury LS et al. (1997) The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J 16: 5966-76 PubMed GONUTS page
- ↑ Cocker JH et al. (1996) An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast. Nature 379: 180-2 PubMed GONUTS page
- ↑ Aparicio OM et al. (1997) Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase. Cell 91: 59-69 PubMed GONUTS page
- ↑ Fujita M et al. (1998) Cell cycle dependent topological changes of chromosomal replication origins in Saccharomyces cerevisiae. Genes Cells 3: 737-49 PubMed GONUTS page
- ↑ Zou L & Stillman B (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280: 593-6 PubMed GONUTS page
- ↑ Rehman MA et al. (2006) Differential requirement of DNA replication factors for subtelomeric ARS consensus sequence protosilencers in Saccharomyces cerevisiae. Genetics 174: 1801-10 PubMed GONUTS page
