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SGD:CDC5
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | CDC5 ( synonyms: YMR001C, MSD2, PKX2 ) | |
| Protein Name(s) | Polo-like kinase with multiple functions in mitosis and cytokinesis, | |
| External Links | ||
| SGD | S000004603 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0000712 |
resolution of meiotic recombination intermediates |
SGD_REF:S000079360 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000922 |
spindle pole |
SGD_REF:S000050961 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000052953 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000052953 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000068838 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000113918 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000119737 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000119737 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0004672 |
protein kinase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0723 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000047786 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005935 |
cellular bud neck |
SGD_REF:S000050961 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000052953 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000052953 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000113918 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000119737 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000119737 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006468 |
protein phosphorylation |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0007067 |
mitosis |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0498 |
P |
From SGD |
||
| GO:0010696 |
positive regulation of spindle pole body separation |
SGD_REF:S000126537 |
IGI: Inferred from Genetic Interaction |
SGD:S000006188 |
P |
From SGD |
||
| GO:0010696 |
positive regulation of spindle pole body separation |
SGD_REF:S000126537 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016301 |
kinase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From SGD |
||
| GO:0016310 |
phosphorylation |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From SGD |
||
| GO:0016740 |
transferase activity |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From SGD |
||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
||
| GO:0070194 |
synaptonemal complex disassembly |
SGD_REF:S000127922 |
IGI: Inferred from Genetic Interaction |
SGD:S000001166 |
P |
From SGD |
||
| GO:0090306 |
spindle assembly involved in meiosis |
SGD_REF:S000133454 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Clyne RK et al. (2003) Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I. Nat Cell Biol 5: 480-5 PubMed GONUTS page
- ↑ 2.0 2.1 Song S et al. (2000) Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures. Mol Cell Biol 20: 286-98 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Kitada K et al. (1993) A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol Cell Biol 13: 4445-57 PubMed GONUTS page
- ↑ Geymonat M et al. (2003) In vitro regulation of budding yeast Bfa1/Bub2 GAP activity by Cdc5. J Biol Chem 278: 14591-4 PubMed GONUTS page
- ↑ 5.0 5.1 Ptacek J et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438: 679-84 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Darieva Z et al. (2006) Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator protein. Nature 444: 494-8 PubMed GONUTS page
- ↑ Cheng L et al. (1998) Cell cycle regulation of the Saccharomyces cerevisiae polo-like kinase cdc5p. Mol Cell Biol 18: 7360-70 PubMed GONUTS page
- ↑ 8.0 8.1 Crasta K et al. (2008) Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle. Nat Cell Biol 10: 665-75 PubMed GONUTS page
- ↑ Sourirajan A & Lichten M (2008) Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev 22: 2627-32 PubMed GONUTS page
- ↑ Iacovella MG et al. (2010) Analysis of Polo-like kinase Cdc5 in the meiosis recombination checkpoint. Cell Cycle 9: 1182-93 PubMed GONUTS page
