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SGD:CDC4
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | CDC4 ( synonyms: YFL009W ) | |
| Protein Name(s) | F-box protein required for G1/S and G2/M transition, | |
| External Links | ||
| SGD | S000001885 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000082 |
G1/S transition of mitotic cell cycle |
SGD_REF:S000045265 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
SGD_REF:S000043548 |
IGI: Inferred from Genetic Interaction |
SGD:S000004069 |
P |
From SGD |
||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
SGD_REF:S000045265 |
IGI: Inferred from Genetic Interaction |
P |
From SGD |
|||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
SGD_REF:S000045265 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000059560 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0007067 |
mitosis |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0498 |
P |
From SGD |
||
| GO:0007126 |
meiosis |
SGD_REF:S000055075 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0016363 |
nuclear matrix |
SGD_REF:S000048233 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
SGD_REF:S000041398 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
SGD_REF:S000041398 |
IPI: Inferred from Physical Interaction |
SGD:S000002290 |
C |
From SGD |
||
| GO:0019005 |
SCF ubiquitin ligase complex |
SGD_REF:S000058226 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
SGD_REF:S000058226 |
IPI: Inferred from Physical Interaction |
SGD:S000002736 |
C |
From SGD |
||
| GO:0030435 |
sporulation resulting in formation of a cellular spore |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0749 |
P |
From SGD |
||
| GO:0031146 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
SGD_REF:S000041398 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0031146 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
SGD_REF:S000058226 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
SGD_REF:S000041398 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
SGD_REF:S000058226 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0043130 |
ubiquitin binding |
SGD_REF:S000142457 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0043224 |
nuclear SCF ubiquitin ligase complex |
SGD_REF:S000059560 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
||
|
contributes_to |
GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000041398 |
IDA: Inferred from Direct Assay |
F |
From SGD |
||
|
contributes_to |
GO:0004842 |
ubiquitin-protein ligase activity |
SGD_REF:S000058226 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Goh PY & Surana U (1999) Cdc4, a protein required for the onset of S phase, serves an essential function during G(2)/M transition in Saccharomyces cerevisiae. Mol Cell Biol 19: 5512-22 PubMed GONUTS page
- ↑ Schwob E et al. (1994) The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79: 233-44 PubMed GONUTS page
- ↑ 3.0 3.1 Blondel M et al. (2000) Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4. EMBO J 19: 6085-97 PubMed GONUTS page
- ↑ Simchen G & Hirschberg J (1977) Effects of the mitotic cell-cycle mutation cdc4 on yeast meiosis. Genetics 86: 57-72 PubMed GONUTS page
- ↑ Choi WJ et al. (1990) The CDC4 gene product is associated with the yeast nuclear skeleton. Biochem Biophys Res Commun 172: 1324-30 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Feldman RM et al. (1997) A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91: 221-30 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Skowyra D et al. (1997) F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91: 209-19 PubMed GONUTS page
- ↑ Pashkova N et al. (2010) WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins. Mol Cell 40: 433-43 PubMed GONUTS page
