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SGD:CDC12
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | CDC12 ( synonyms: YHR107C, CLA10, PSL7 ) | |
| Protein Name(s) | Component of the septin ring that is required for cytokinesis, | |
| External Links | ||
| SGD | S000001149 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000144 |
cellular bud neck septin ring |
SGD_REF:S000055476 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From SGD |
||
| GO:0000921 |
septin ring assembly |
SGD_REF:S000077127 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0003924 |
GTPase activity |
SGD_REF:S000077127 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005198 |
structural molecule activity |
SGD_REF:S000126669 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000121415 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005525 |
GTP binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0342 |
F |
From SGD |
||
| GO:0005545 |
1-phosphatidylinositol binding |
SGD_REF:S000072964 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005737 |
cytoplasm |
SGD_REF:S000069459 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005935 |
cellular bud neck |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0029 |
C |
From SGD |
||
| GO:0005937 |
mating projection |
SGD_REF:S000126719 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0007049 |
cell cycle |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From SGD |
||
| GO:0016020 |
membrane |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0162 |
C |
From SGD |
||
| GO:0030011 |
maintenance of cell polarity |
SGD_REF:S000044053 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0031105 |
septin complex |
SGD_REF:S000052983 |
IPI: Inferred from Physical Interaction |
SGD:S000004306 |
C |
From SGD |
||
| GO:0031105 |
septin complex |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0031105 |
septin complex |
SGD_REF:S000126669 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0032160 |
septin filament array |
SGD_REF:S000077562 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0032947 |
protein complex scaffold |
SGD_REF:S000039417 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0033205 |
cell cycle cytokinesis |
SGD_REF:S000073001 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0045860 |
positive regulation of protein kinase activity |
SGD_REF:S000074229 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0051301 |
cell division |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Haarer BK & Pringle JR (1987) Immunofluorescence localization of the Saccharomyces cerevisiae CDC12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck. Mol Cell Biol 7: 3678-87 PubMed GONUTS page
- ↑ 2.0 2.1 Versele M & Thorner J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol 164: 701-15 PubMed GONUTS page
- ↑ 3.0 3.1 Bertin A et al. (2008) Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proc Natl Acad Sci U S A 105: 8274-9 PubMed GONUTS page
- ↑ Vrabioiu AM et al. (2004) The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J Biol Chem 279: 3111-8 PubMed GONUTS page
- ↑ Casamayor A & Snyder M (2003) Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function. Mol Cell Biol 23: 2762-77 PubMed GONUTS page
- ↑ Kumar A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16: 707-19 PubMed GONUTS page
- ↑ Bharucha JP et al. (2008) Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryot Cell 7: 1246-55 PubMed GONUTS page
- ↑ Barral Y et al. (2000) Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast. Mol Cell 5: 841-51 PubMed GONUTS page
- ↑ Frazier JA et al. (1998) Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. J Cell Biol 143: 737-49 PubMed GONUTS page
- ↑ Versele M et al. (2004) Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Mol Biol Cell 15: 4568-83 PubMed GONUTS page
- ↑ Lippincott J & Li R (1998) Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis. J Cell Biol 140: 355-66 PubMed GONUTS page
- ↑ Dobbelaere J et al. (2003) Phosphorylation-dependent regulation of septin dynamics during the cell cycle. Dev Cell 4: 345-57 PubMed GONUTS page
- ↑ Hanrahan J & Snyder M (2003) Cytoskeletal activation of a checkpoint kinase. Mol Cell 12: 663-73 PubMed GONUTS page
