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SGD:BLM10

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) BLM10 ( synonyms: YFL007W, YFL006W )
Protein Name(s) Proteasome activator,
External Links
SGD S000001887

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005634

nucleus

SGD_REF:S000076318
PMID:12973301[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000081108
PMID:15778719[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000114049
PMID:12192589[3]

ISM: Inferred from Sequence Model

C

From SGD

GO:0016504

peptidase activator activity

SGD_REF:S000147225
PMID:22025621[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0043248

proteasome assembly

SGD_REF:S000076318
PMID:12973301[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043248

proteasome assembly

SGD_REF:S000124287
PMID:17911101[5]

IGI: Inferred from Genetic Interaction

SGD:S000001946
SGD:S000001337

P

From SGD

GO:0061136

regulation of proteasomal protein catabolic process

SGD_REF:S000147225
PMID:22025621[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0070628

proteasome binding

SGD_REF:S000147225
PMID:22025621[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0070628

proteasome binding

SGD_REF:S000147225
PMID:22025621[4]

IMP: Inferred from Mutant Phenotype

F

From SGD

colocalizes_with

GO:0000502

proteasome complex

SGD_REF:S000081108
PMID:15778719[2]

IDA: Inferred from Direct Assay

C

From SGD

colocalizes_with

GO:0005839

proteasome core complex

SGD_REF:S000081108
PMID:15778719[2]

IDA: Inferred from Direct Assay

C

From SGD

colocalizes_with

GO:0005839

proteasome core complex

SGD_REF:S000081108
PMID:15778719[2]

IMP: Inferred from Mutant Phenotype

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Fehlker M et al. (2003) Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly. EMBO Rep 4: 959-63 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Schmidt M et al. (2005) The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle. Nat Struct Mol Biol 12: 294-303 PubMed GONUTS page
  3. De Hertogh B et al. (2002) Phylogenetic classification of transporters and other membrane proteins from Saccharomyces cerevisiae. Funct Integr Genomics 2: 154-70 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Dange T et al. (2011) Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism. J Biol Chem 286: 42830-9 PubMed GONUTS page
  5. Marques AJ et al. (2007) The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturation. J Biol Chem 282: 34869-76 PubMed GONUTS page
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