SGD:ASK1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ASK1 ( synonyms: YKL052C )
Protein Name(s) Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation,
External Links
SGD S000001535

Annotations

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0000278

mitotic cell cycle

SGD_REF:S000131114

P

From SGD

GO:0000279

M phase

SGD_REF:S000131114

P

From SGD

GO:0000777

condensed chromosome kinetochore

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0149

C

From SGD

GO:0000778

condensed nuclear chromosome kinetochore

SGD_REF:S000069091
PMID:11756468[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000780

condensed nuclear chromosome, centromeric region

SGD_REF:S000069220
PMID:11782438[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000922

spindle pole

SGD_REF:S000127119
PMID:18613951[3]

C

From SGD

GO:0005200

structural constituent of cytoskeleton

SGD_REF:S000069091
PMID:11756468[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005634

nucleus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

From SGD

GO:0005815

microtubule organizing center

SGD_REF:S000127119
PMID:18613951[3]

C

From SGD

GO:0005816

spindle pole body

SGD_REF:S000127119
PMID:18613951[3]

C

From SGD

GO:0005819

spindle

SGD_REF:S000069091
PMID:11756468[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005819

spindle

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0251

C

From SGD

GO:0005874

microtubule

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0493

C

From SGD

GO:0007049

cell cycle

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

From SGD

GO:0007059

chromosome segregation

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0159

P

From SGD

GO:0007067

mitosis

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0498

P

From SGD

GO:0030472

mitotic spindle organization in nucleus

SGD_REF:S000069091
PMID:11756468[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[4]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[5]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[6]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[4]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0048285

organelle fission

SGD_REF:S000131114

P

From SGD

GO:0051301

cell division

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0132

P

From SGD


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Cheeseman IM et al. (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J Cell Biol 155: 1137-45 PubMed GONUTS page
  2. Janke C et al. (2002) Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J 21: 181-93 PubMed GONUTS page
  3. 3.0 3.1 3.2 Tian W et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1: S7 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Westermann S et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17: 277-90 PubMed GONUTS page
  5. 5.0 5.1 Li Y et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16: 183-97 PubMed GONUTS page
  6. 6.0 6.1 Miranda JJ et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12: 138-43 PubMed GONUTS page
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