SGD:ASH1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ASH1 ( synonyms: YKL185W )
Protein Name(s) Zinc-finger inhibitor of HO transcription,
External Links
SGD S000001668

Annotations

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000079870
PMID:11171979[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0003677

DNA binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

From SGD

GO:0003700

transcription factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From SGD

GO:0003700

transcription factor activity

SGD_REF:S000127119
PMID:18613951[2]

F

From SGD

GO:0003704

specific RNA polymerase II transcription factor activity

SGD_REF:S000059111
PMID:11046133[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003704

specific RNA polymerase II transcription factor activity

SGD_REF:S000059111
PMID:11046133[3]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0005634

nucleus

SGD_REF:S000042424
PMID:8625408[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000042425
PMID:8625409[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000045535
PMID:9566907[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

C

From SGD

GO:0005634

nucleus

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000125578

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

From SGD

GO:0005933

cellular bud

SGD_REF:S000042425
PMID:8625409[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006350

transcription

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

P

From SGD

GO:0007124

pseudohyphal growth

SGD_REF:S000045535
PMID:9566907[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007124

pseudohyphal growth

SGD_REF:S000059111
PMID:11046133[3]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0007124

pseudohyphal growth

SGD_REF:S000059111
PMID:11046133[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0862

F

From SGD

GO:0008298

intracellular mRNA localization

SGD_REF:S000131114

P

From SGD

GO:0016566

specific transcriptional repressor activity

SGD_REF:S000042424
PMID:8625408[4]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0016566

specific transcriptional repressor activity

SGD_REF:S000042425
PMID:8625409[5]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0016566

specific transcriptional repressor activity

SGD_REF:S000079870
PMID:11171979[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0016568

chromatin modification

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0156

P

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113697
PMID:16314178[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000128493
PMID:19040720[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000127119
PMID:18613951[2]

F

From SGD

GO:0045449

regulation of transcription

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

From SGD

GO:0045894

negative regulation of transcription, mating-type specific

SGD_REF:S000042424
PMID:8625408[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0046872

metal ion binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

From SGD

GO:0070210

Rpd3L-Expanded complex

SGD_REF:S000128493
PMID:19040720[8]

IDA: Inferred from Direct Assay

C

From SGD

contributes_to

GO:0004407

histone deacetylase activity

SGD_REF:S000113697
PMID:16314178[7]

IDA: Inferred from Direct Assay

F

From SGD


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Maxon ME & Herskowitz I (2001) Ash1p is a site-specific DNA-binding protein that actively represses transcription. Proc Natl Acad Sci U S A 98: 1495-500 PubMed GONUTS page
  2. 2.0 2.1 Tian W et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1: S7 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Pan X & Heitman J (2000) Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion. Mol Cell Biol 20: 8364-72 PubMed GONUTS page
  4. 4.0 4.1 4.2 Bobola N et al. (1996) Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells. Cell 84: 699-709 PubMed GONUTS page
  5. 5.0 5.1 5.2 Sil A & Herskowitz I (1996) Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene. Cell 84: 711-22 PubMed GONUTS page
  6. 6.0 6.1 Chandarlapaty S & Errede B (1998) Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae. Mol Cell Biol 18: 2884-91 PubMed GONUTS page
  7. 7.0 7.1 Carrozza MJ et al. (2005) Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta 1731: 77-87; discussion 75-6 PubMed GONUTS page
  8. 8.0 8.1 Shevchenko A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9: R167 PubMed GONUTS page
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