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SGD:AFG3
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | AFG3 ( synonyms: YER017C, YTA10 ) | |
| Protein Name(s) | Component of the mitochondrial inner membrane m-AAA protease, | |
| External Links | ||
| SGD | S000000819 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0000166 |
nucleotide binding |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0004222 |
metalloendopeptidase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005515 |
protein binding |
SGD_REF:S000134962 |
IPI: Inferred from Physical Interaction |
SGD:S000004695 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR003960 |
F |
From SGD |
||
| GO:0005524 |
ATP binding |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0005524 |
ATP binding |
SGD_REF:S000134962 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000117178 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005739 |
mitochondrion |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0005743 |
mitochondrial inner membrane |
SGD_REF:S000050177 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005745 |
m-AAA complex |
SGD_REF:S000055187 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006461 |
protein complex assembly |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006465 |
signal peptide processing |
SGD_REF:S000071826 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0006508 |
proteolysis |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0008233 |
peptidase activity |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0008237 |
metallopeptidase activity |
SGD_REF:S000055187 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0008237 |
metallopeptidase activity |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016020 |
membrane |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016021 |
integral to membrane |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
C |
From SGD |
|||
| GO:0016787 |
hydrolase activity |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016887 |
ATPase activity |
SGD_REF:S000053170 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From SGD |
|||
| GO:0016887 |
ATPase activity |
SGD_REF:S000134962 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0016887 |
ATPase activity |
SGD_REF:S000134962 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0017111 |
nucleoside-triphosphatase activity |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0030163 |
protein catabolic process |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
P |
From SGD |
|||
| GO:0031966 |
mitochondrial membrane |
SGD_REF:S000125578 |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0171 |
C |
From SGD |
||
| GO:0045041 |
protein import into mitochondrial intermembrane space |
SGD_REF:S000071826 |
TAS: Traceable Author Statement |
P |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000124038 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0097002 |
mitochondrial inner boundary membrane |
SGD_REF:S000128411 |
IDA: Inferred from Direct Assay |
C |
From SGD |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Augustin S et al. (2009) An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell 35: 574-85 PubMed GONUTS page
- ↑ Reinders J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5: 1543-54 PubMed GONUTS page
- ↑ Tauer R et al. (1994) Yta10p, a member of a novel ATPase family in yeast, is essential for mitochondrial function. FEBS Lett 353: 197-200 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Arlt H et al. (1996) The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 85: 875-85 PubMed GONUTS page
- ↑ 5.0 5.1 Esser K et al. (2002) A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. J Mol Biol 323: 835-43 PubMed GONUTS page
- ↑ Guelin E et al. (1994) Sequence of the AFG3 gene encoding a new member of the FtsH/Yme1/Tma subfamily of the AAA-protein family. Yeast 10: 1389-94 PubMed GONUTS page
- ↑ Suppanz IE et al. (2009) The m-AAA protease processes cytochrome c peroxidase preferentially at the inner boundary membrane of mitochondria. Mol Biol Cell 20: 572-80 PubMed GONUTS page
