SGD:ADE1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ADE1 ( synonyms: YAR015W )
Protein Name(s) N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis,
External Links
SGD S000000070

Annotations

QualifierGO IDGO term nameReference(s)Evidence Codewith/fromAspectNotesStatus
GO:0000166

nucleotide binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

From SGD

GO:0003824

catalytic activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

From SGD

GO:0004639

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

SGD_REF:S000039345
PMID:1756975[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004639

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

SGD_REF:S000120854
PMID:5767024[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004639

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

SGD_REF:S000120856
PMID:5767025[3]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004639

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001636
InterPro:IPR018236

F

From SGD

GO:0004639

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:6.3.2.6

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000074185
PMID:14562095[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000074185
PMID:14562095[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006164

purine nucleotide biosynthetic process

SGD_REF:S000039345
PMID:1756975[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006164

purine nucleotide biosynthetic process

SGD_REF:S000120854
PMID:5767024[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006164

purine nucleotide biosynthetic process

SGD_REF:S000120856
PMID:5767025[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006164

purine nucleotide biosynthetic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001636
InterPro:IPR018236

P

From SGD

GO:0006164

purine nucleotide biosynthetic process

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0658

P

From SGD

GO:0006189

'de novo' IMP biosynthetic process

SGD_REF:S000039345
PMID:1756975[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006189

'de novo' IMP biosynthetic process

SGD_REF:S000120854
PMID:5767024[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006189

'de novo' IMP biosynthetic process

SGD_REF:S000120856
PMID:5767025[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016874

ligase activity

SGD_REF:S000124038

IEA: Inferred from Electronic Annotation

SP_KW:KW-0436

F

From SGD

GO:0018193

peptidyl-amino acid modification

SGD_REF:S000131114

P

From SGD

GO:0042493

response to drug

SGD_REF:S000086944
PMID:16234568[5]

IMP: Inferred from Mutant Phenotype

P

From SGD


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Myasnikov AN et al. (1991) The Saccharomyces cerevisiae ADE1 gene: structure, overexpression and possible regulation by general amino acid control. Gene 109: 143-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 Silver JM & Eaton NR (1969) Functional blocks of the ad-1 and ad-2 mutants of Saccharomyces cerevisiae. Biochem Biophys Res Commun 34: 301-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 Fisher CR (1969) Enzymology of the pigmented adenine-requiring mutants of Saccharomyces and Schizosaccharomyces. Biochem Biophys Res Commun 34: 306-10 PubMed GONUTS page
  4. 4.0 4.1 Huh WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425: 686-91 PubMed GONUTS page
  5. Dilda PJ et al. (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97: 1539-47 PubMed GONUTS page
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