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SGD:ADA2
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (baker's yeast) (taxon:4932) | |
| Gene Name(s) | ADA2 ( synonyms: YDR448W, SWI8 ) | |
| Protein Name(s) | Transcription coactivator, | |
| External Links | ||
| SGD | S000002856 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000124 |
SAGA complex |
SGD_REF:S000045957 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000124 |
SAGA complex |
SGD_REF:S000048255 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0000183 |
chromatin silencing at rDNA |
SGD_REF:S000132194 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0001786 |
phosphatidylserine binding |
SGD_REF:S000128154 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0001786 |
phosphatidylserine binding |
SGD_REF:S000128154 |
IMP: Inferred from Mutant Phenotype |
F |
From SGD |
|||
| GO:0003677 |
DNA binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0003682 |
chromatin binding |
SGD_REF:S000132194 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0003713 |
transcription coactivator activity |
SGD_REF:S000043194 |
IDA: Inferred from Direct Assay |
F |
From SGD |
|||
| GO:0005634 |
nucleus |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From SGD |
||
| GO:0005634 |
nucleus |
SGD_REF:S000148671 |
IEA: Inferred from Electronic Annotation |
UniProtKB-SubCell:SL-0191 |
C |
From SGD |
||
| GO:0005671 |
Ada2/Gcn5/Ada3 transcription activator complex |
SGD_REF:S000042121 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0005671 |
Ada2/Gcn5/Ada3 transcription activator complex |
SGD_REF:S000057512 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0006348 |
chromatin silencing at telomere |
SGD_REF:S000132194 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0006351 |
transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From SGD |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From SGD |
||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
SGD_REF:S000128154 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0008270 |
zinc ion binding |
SGD_REF:S000124036 |
IEA: Inferred from Electronic Annotation |
F |
From SGD |
|||
| GO:0016568 |
chromatin modification |
SGD_REF:S000048255 |
IDA: Inferred from Direct Assay |
P |
From SGD |
|||
| GO:0035066 |
positive regulation of histone acetylation |
SGD_REF:S000071702 |
IMP: Inferred from Mutant Phenotype |
P |
From SGD |
|||
| GO:0046695 |
SLIK (SAGA-like) complex |
SGD_REF:S000071997 |
IDA: Inferred from Direct Assay |
C |
From SGD |
|||
| GO:0046872 |
metal ion binding |
SGD_REF:S000148669 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From SGD |
||
|
contributes_to |
GO:0004402 |
histone acetyltransferase activity |
SGD_REF:S000074492 |
IDA: Inferred from Direct Assay |
F |
From SGD |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Grant PA et al. (1997) Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev 11: 1640-50 PubMed GONUTS page
- ↑ 2.0 2.1 Grant PA et al. (1998) A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94: 45-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Jacobson S & Pillus L (2009) The SAGA subunit Ada2 functions in transcriptional silencing. Mol Cell Biol 29: 6033-45 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Hoke SM et al. (2008) A conserved central region of yeast Ada2 regulates the histone acetyltransferase activity of Gcn5 and interacts with phospholipids. J Mol Biol 384: 743-55 PubMed GONUTS page
- ↑ Silverman N et al. (1994) Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. Proc Natl Acad Sci U S A 91: 11665-8 PubMed GONUTS page
- ↑ Eberharter A et al. (1999) The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Mol Cell Biol 19: 6621-31 PubMed GONUTS page
- ↑ Horiuchi J et al. (1995) ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex. Mol Cell Biol 15: 1203-9 PubMed GONUTS page
- ↑ Boyer LA et al. (2002) Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol Cell 10: 935-42 PubMed GONUTS page
- ↑ Pray-Grant MG et al. (2002) The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol Cell Biol 22: 8774-86 PubMed GONUTS page
- ↑ Balasubramanian R et al. (2002) Role of the Ada2 and Ada3 transcriptional coactivators in histone acetylation. J Biol Chem 277: 7989-95 PubMed GONUTS page
