SGD:ABF1

From GONUTS

Species (Taxon ID)	Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s)	ABF1 ( synonyms: YKL112W, BAF1, OBF1, REB2, SBF1 )
Protein Name(s)	DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair,
External Links
SGD	S000001595

Annotations

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes
	GO:0000113	nucleotide-excision repair factor 4 complex	SGD_REF:S000056193 PMID:10601031^[1]	IPI: Inferred from Physical Interaction	SGD:S000003813	C	From SGD
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	SGD_REF:S000076894 PMID:15192094^[2]	IMP: Inferred from Mutant Phenotype		P	From SGD
	GO:0000715	nucleotide-excision repair, DNA damage recognition	SGD_REF:S000056193 PMID:10601031^[1]	IMP: Inferred from Mutant Phenotype		P	From SGD
	GO:0000715	nucleotide-excision repair, DNA damage recognition	SGD_REF:S000056193 PMID:10601031^[1]	IPI: Inferred from Physical Interaction	SGD:S000003813	P	From SGD
	GO:0000715	nucleotide-excision repair, DNA damage recognition	SGD_REF:S000077426 PMID:15177043^[3]	IDA: Inferred from Direct Assay		P	From SGD
	GO:0000790	nuclear chromatin	SGD_REF:S000069013 PMID:11756546^[4]	TAS: Traceable Author Statement		C	From SGD
	GO:0003677	DNA binding	SGD_REF:S000050312 PMID:3275867^[5]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0003677	DNA binding	SGD_REF:S000124036	IEA: Inferred from Electronic Annotation	InterPro:IPR006774	F	From SGD
	GO:0003677	DNA binding	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	From SGD
	GO:0003682	chromatin binding	SGD_REF:S000040971 PMID:10684934^[6]	IMP: Inferred from Mutant Phenotype		F	From SGD
	GO:0003682	chromatin binding	SGD_REF:S000077502 PMID:15456886^[7]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0003688	DNA replication origin binding	SGD_REF:S000117043 PMID:16824194^[8]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0005634	nucleus	SGD_REF:S000080227 PMID:15522095^[9]	IDA: Inferred from Direct Assay		C	From SGD
	GO:0005634	nucleus	SGD_REF:S000080227 PMID:15522095^[9]	IMP: Inferred from Mutant Phenotype		C	From SGD
	GO:0005634	nucleus	SGD_REF:S000124036	IEA: Inferred from Electronic Annotation	InterPro:IPR006774	C	From SGD
	GO:0005634	nucleus	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C	From SGD
	GO:0005634	nucleus	SGD_REF:S000125578	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C	From SGD
	GO:0006260	DNA replication	SGD_REF:S000069013 PMID:11756546^[4]	IDA: Inferred from Direct Assay		P	From SGD
	GO:0006260	DNA replication	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0235	P	From SGD
	GO:0006338	chromatin remodeling	SGD_REF:S000040971 PMID:10684934^[6]	IMP: Inferred from Mutant Phenotype		P	From SGD
	GO:0006338	chromatin remodeling	SGD_REF:S000124036	IEA: Inferred from Electronic Annotation	InterPro:IPR006774	P	From SGD
	GO:0006350	transcription	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P	From SGD
	GO:0008270	zinc ion binding	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0862	F	From SGD
	GO:0008301	DNA bending activity	SGD_REF:S000053200 PMID:8206955^[10]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0016563	transcription activator activity	SGD_REF:S000069013 PMID:11756546^[4]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0016563	transcription activator activity	SGD_REF:S000076894 PMID:15192094^[2]	IMP: Inferred from Mutant Phenotype		F	From SGD
	GO:0016564	transcription repressor activity	SGD_REF:S000076894 PMID:15192094^[2]	IMP: Inferred from Mutant Phenotype		F	From SGD
	GO:0030466	chromatin silencing at silent mating-type cassette	SGD_REF:S000053123 PMID:8582634^[11]	IMP: Inferred from Mutant Phenotype		P	From SGD
	GO:0043565	sequence-specific DNA binding	SGD_REF:S000128778 PMID:19111667^[12]	IDA: Inferred from Direct Assay		F	From SGD
	GO:0045449	regulation of transcription	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P	From SGD
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	SGD_REF:S000076894 PMID:15192094^[2]	IMP: Inferred from Mutant Phenotype		P	From SGD
	GO:0046872	metal ion binding	SGD_REF:S000124038	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	From SGD
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Reed SH et al. (1999) Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. Genes Dev 13: 3052-8 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Miyake T et al. (2004) Genome-wide analysis of ARS (autonomously replicating sequence) binding factor 1 (Abf1p)-mediated transcriptional regulation in Saccharomyces cerevisiae. J Biol Chem 279: 34865-72 PubMed GONUTS page
↑ Yu S et al. (2004) The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. DNA Repair (Amst) 3: 277-87 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Miyake T et al. (2002) Identification of a multifunctional domain in autonomously replicating sequence-binding factor 1 required for transcriptional activation, DNA replication, and gene silencing. Mol Cell Biol 22: 505-16 PubMed GONUTS page
↑ Buchman AR et al. (1988) Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol Cell Biol 8: 210-25 PubMed GONUTS page
↑ ^6.0 ^6.1 Lascaris RF et al. (2000) Different roles for abf1p and a T-rich promoter element in nucleosome organization of the yeast RPS28A gene. Nucleic Acids Res 28: 1390-6 PubMed GONUTS page
↑ Yarragudi A et al. (2004) Comparison of ABF1 and RAP1 in chromatin opening and transactivator potentiation in the budding yeast Saccharomyces cerevisiae. Mol Cell Biol 24: 9152-64 PubMed GONUTS page
↑ Kawasaki Y et al. (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11: 745-56 PubMed GONUTS page
↑ ^9.0 ^9.1 Loch CM et al. (2004) Functional and physical interactions between autonomously replicating sequence-binding factor 1 and the nuclear transport machinery. Traffic 5: 925-35 PubMed GONUTS page
↑ McBroom LD & Sadowski PD (1994) DNA bending by Saccharomyces cerevisiae ABF1 and its proteolytic fragments. J Biol Chem 269: 16461-8 PubMed GONUTS page
↑ Loo S et al. (1995) Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae. Genetics 141: 889-902 PubMed GONUTS page
↑ Badis G et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32: 878-87 PubMed GONUTS page

[PMID:10601031-0] 1.0 ^1.1 ^1.2 Reed SH et al. (1999) Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. Genes Dev 13: 3052-8 PubMed GONUTS page

[PMID:15192094-1] 2.0 ^2.1 ^2.2 ^2.3 Miyake T et al. (2004) Genome-wide analysis of ARS (autonomously replicating sequence) binding factor 1 (Abf1p)-mediated transcriptional regulation in Saccharomyces cerevisiae. J Biol Chem 279: 34865-72 PubMed GONUTS page

[PMID:15177043-2] Yu S et al. (2004) The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair. DNA Repair (Amst) 3: 277-87 PubMed GONUTS page

[PMID:11756546-3] 4.0 ^4.1 ^4.2 Miyake T et al. (2002) Identification of a multifunctional domain in autonomously replicating sequence-binding factor 1 required for transcriptional activation, DNA replication, and gene silencing. Mol Cell Biol 22: 505-16 PubMed GONUTS page

[PMID:3275867-4] Buchman AR et al. (1988) Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol Cell Biol 8: 210-25 PubMed GONUTS page

[PMID:10684934-5] 6.0 ^6.1 Lascaris RF et al. (2000) Different roles for abf1p and a T-rich promoter element in nucleosome organization of the yeast RPS28A gene. Nucleic Acids Res 28: 1390-6 PubMed GONUTS page

[PMID:15456886-6] Yarragudi A et al. (2004) Comparison of ABF1 and RAP1 in chromatin opening and transactivator potentiation in the budding yeast Saccharomyces cerevisiae. Mol Cell Biol 24: 9152-64 PubMed GONUTS page

[PMID:16824194-7] Kawasaki Y et al. (2006) Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells 11: 745-56 PubMed GONUTS page

[PMID:15522095-8] 9.0 ^9.1 Loch CM et al. (2004) Functional and physical interactions between autonomously replicating sequence-binding factor 1 and the nuclear transport machinery. Traffic 5: 925-35 PubMed GONUTS page

[PMID:8206955-9] McBroom LD & Sadowski PD (1994) DNA bending by Saccharomyces cerevisiae ABF1 and its proteolytic fragments. J Biol Chem 269: 16461-8 PubMed GONUTS page

[PMID:8582634-10] Loo S et al. (1995) Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae. Genetics 141: 889-902 PubMed GONUTS page

[PMID:19111667-11] Badis G et al. (2008) A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell 32: 878-87 PubMed GONUTS page

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SGD:ABF1

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