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SCHPO:SAP1
Contents |
| Species (Taxon ID) | Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast). (taxon:284812) | |
| Gene Name(s) | sap1 | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | SAP1_SCHPO | |
| UniProt Accessions | P40847, P78961, | |
| EMBL | X77578, CU329672, | |
| PIR | A56214, T45515, | |
| RefSeq | NP_587873.1, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0042803 |
protein homodimerization activity |
TAS: Traceable Author Statement |
|
F |
||||
| GO:0007059 |
chromosome segregation |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0043110 |
rDNA spacer replication fork barrier binding |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0051276 |
chromosome organization |
IMP: Inferred from Mutant Phenotype |
|
P |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0000790 |
nuclear chromatin |
TAS: Traceable Author Statement |
|
C |
||||
| GO:0008301 |
DNA bending activity |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0043110 |
rDNA spacer replication fork barrier binding |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0007126 |
meiosis |
NAS: Non-traceable Author Statement |
|
P |
||||
| GO:0071170 |
site-specific DNA replication termination |
IDA: Inferred from Direct Assay |
|
P |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0000728 |
gene conversion at mating-type locus, DNA double-strand break formation |
IMP: Inferred from Mutant Phenotype |
|
P |
||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0031582 |
replication fork arrest at rDNA repeats |
IDA: Inferred from Direct Assay |
|
P |
||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0031582 |
replication fork arrest at rDNA repeats |
IMP: Inferred from Mutant Phenotype |
|
P |
||||
| GO:0008156 |
negative regulation of DNA replication |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 1 |
complete | |||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
|
C |
||||
| GO:0000728 |
gene conversion at mating-type locus, DNA double-strand break formation |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0000790 |
nuclear chromatin |
TAS: Traceable Author Statement |
C |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0003677 |
DNA binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
||||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0007059 |
chromosome segregation |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0008301 |
DNA bending activity |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0031582 |
replication fork arrest at rDNA repeats |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0031582 |
replication fork arrest at rDNA repeats |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0042803 |
protein homodimerization activity |
TAS: Traceable Author Statement |
F |
|||||
| GO:0043110 |
rDNA spacer replication fork barrier binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0043110 |
rDNA spacer replication fork barrier binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0051276 |
chromosome organization |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0071170 |
site-specific DNA replication termination |
IDA: Inferred from Direct Assay |
P |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Mejía-Ramírez E et al. (2005) The mating type switch-activating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast. Mol Cell Biol 25: 8755-61 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 de Lahondès R et al. (2003) Fission yeast Sap1 protein is essential for chromosome stability. Eukaryot Cell 2: 910-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Krings G & Bastia D (2005) Sap1p binds to Ter1 at the ribosomal DNA of Schizosaccharomyces pombe and causes polar replication fork arrest. J Biol Chem 280: 39135-42 PubMed GONUTS page
- ↑ Aslett M & Wood V (2006) Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%. Yeast 23: 913-9 PubMed GONUTS page
- ↑ 5.0 5.1 Arcangioli B & Klar AJ (1991) A novel switch-activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe. EMBO J 10: 3025-32 PubMed GONUTS page
- ↑ 6.0 6.1 Arcangioli B et al. (1994) Identification of the DNA-binding domains of the switch-activating-protein Sap1 from S.pombe by random point mutations screening in E.coli. Nucleic Acids Res 22: 2930-7 PubMed GONUTS page
- ↑ Zaratiegui M et al. (2011) CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR. Nature 469: 112-5 PubMed GONUTS page
- ↑ 8.0 8.1 Matsuyama A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24: 841-7 PubMed GONUTS page
