SCHPO:MSH6

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Species (Taxon ID)	Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast). (taxon:284812)
Gene Name(s)	msh6
Protein Name(s)	DNA mismatch repair protein msh6
External Links
UniProt Identifier	MSH6_SCHPO
UniProt Accessions	O74502,
EMBL	AF207839, CU329672,
PIR	T41262,
RefSeq	NP_588344.1,
Pfam	PF01624, PF05188, PF05192, PF05190, PF00488,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0005829	cytosol		IDA: Inferred from Direct Assay		C	Source: GeneDB_SPombe
	GO:0005634	nucleus		IDA: Inferred from Direct Assay		C	Source: GeneDB_SPombe
	GO:0043570	maintenance of DNA repeat elements		IMP: Inferred from Mutant Phenotype		P	Source: GeneDB_SPombe
	GO:0006298	mismatch repair		IMP: Inferred from Mutant Phenotype		P	Source: GeneDB_SPombe
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F
	GO:0000228	nuclear chromosome	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN26	C
	GO:0000400	four-way junction DNA binding	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN79	F
	GO:0000710	meiotic mismatch repair	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN26	P
	GO:0003677	DNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F
	GO:0003684	damaged DNA binding	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN24	F
	GO:0005524	ATP binding	GO_REF:0000001	ISS: Inferred from Sequence or Structural Similarity	SGD:S000002504	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016151	F
	GO:0005524	ATP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005634	nucleus	PMID:16823372^[1]	IDA: Inferred from Direct Assay		C
	GO:0005829	cytosol	PMID:16823372^[1]	IDA: Inferred from Direct Assay		C
	GO:0006281	DNA repair	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0234	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016151	P
	GO:0006298	mismatch repair	PMID:11333218^[2]	IMP: Inferred from Mutant Phenotype		P
	GO:0006974	response to DNA damage stimulus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0227	P
	GO:0007131	reciprocal meiotic recombination	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN26	P
	GO:0008094	DNA-dependent ATPase activity	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN24	F
	GO:0009411	response to UV	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN79	P
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016151	F
	GO:0032137	guanine/thymine mispair binding	GO_REF:0000001	ISS: Inferred from Sequence or Structural Similarity	SGD:S000002504	F
	GO:0032138	single base insertion or deletion binding	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN79	F
	GO:0032301	MutSalpha complex	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN79	C
	GO:0043570	maintenance of DNA repeat elements	PMID:11333219^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0045910	negative regulation of DNA recombination	GO_REF:0000033	ISS: Inferred from Sequence or Structural Similarity	PANTHER:PTHR11361_AN79	P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Matsuyama A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24: 841-7 PubMed GONUTS page
↑ Tornier C et al. (2001) Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombe. Genetics 158: 65-75 PubMed GONUTS page
↑ Mansour AA et al. (2001) Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors. Genetics 158: 77-85 PubMed GONUTS page

[PMID:16823372-0] 1.0 ^1.1 Matsuyama A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24: 841-7 PubMed GONUTS page

[PMID:11333218-1] Tornier C et al. (2001) Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombe. Genetics 158: 65-75 PubMed GONUTS page

[PMID:11333219-2] Mansour AA et al. (2001) Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors. Genetics 158: 77-85 PubMed GONUTS page

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SCHPO:MSH6

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