SCHPO:MSH2

From GONUTS

Species (Taxon ID)	Schizosaccharomyces pombe (Fission yeast). (taxon:4896)
Gene Name(s)	msh2
Protein Name(s)	DNA mismatch repair protein msh2
External Links
UniProt Identifier	MSH2_SCHPO
UniProt Accessions	O74773, O42950,
EMBL	AJ006948, CU329671,
PIR	T43699,
RefSeq	XP_001713136.1,
Pfam	PF01624, PF05188, PF05192, PF05190, PF00488,

Annotations

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F
	GO:0003677	DNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011184	F
	GO:0005524	ATP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005634	nucleus	PMID:16823372^[1]	IDA: Inferred from Direct Assay		C
	GO:0005829	cytosol	PMID:16823372^[1]	IDA: Inferred from Direct Assay		C
	GO:0006281	DNA repair	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0234	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	P
	GO:0006298	mismatch repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011184	P
	GO:0006298	mismatch repair	PMID:9858548^[2]	IMP: Inferred from Mutant Phenotype		P
	GO:0006298	mismatch repair	PMID:9871115^[3]	IGI: Inferred from Genetic Interaction		P
	GO:0006974	response to DNA damage stimulus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0227	P
	GO:0007534	gene conversion at mating-type locus	PMID:9858548^[2]	IMP: Inferred from Mutant Phenotype		P
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000432	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007695	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007696	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007860	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007861	F
	GO:0030983	mismatched DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011184	F
	GO:0032301	MutSalpha complex	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011184	C
	GO:0032302	MutSbeta complex	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011184	C
	GO:0043570	maintenance of DNA repeat elements	PMID:11333219^[4]	IMP: Inferred from Mutant Phenotype		P
	GO:0051276	chromosome organization	PMID:9858548^[2]	IMP: Inferred from Mutant Phenotype		P
	GO:0000794	condensed nuclear chromosome	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN26	C	Seeded From PANTHER
	GO:0003006	reproductive developmental process	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN161	P	Seeded From PANTHER
	GO:0003006	reproductive developmental process	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN26	P	Seeded From PANTHER
	GO:0003684	damaged DNA binding	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN159	F	Seeded From PANTHER
	GO:0003684	damaged DNA binding	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN26	F	Seeded From PANTHER
	GO:0005524	ATP binding	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN161	F	Seeded From PANTHER
	GO:0007126	meiosis	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN26	P	Seeded From PANTHER
	GO:0016887	ATPase activity	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN161	F	Seeded From PANTHER
	GO:0016887	ATPase activity	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN24	F	Seeded From PANTHER
	GO:0030983	mismatched DNA binding	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN159	F	Seeded From PANTHER
	GO:0030983	mismatched DNA binding	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN24	F	Seeded From PANTHER
	GO:0032300	mismatch repair complex	PMID:17208035^[5]	ISS: Inferred from Sequence or Structural Similarity	PTHR11361:AN161	C	Seeded From PANTHER
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Matsuyama A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24: 841-7 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Rudolph C et al. (1999) The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization. Mol Cell Biol 19: 241-50 PubMed GONUTS page
↑ Rudolph C et al. (1998) Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1. Curr Genet 34: 343-50 PubMed GONUTS page
↑ Mansour AA et al. (2001) Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors. Genetics 158: 77-85 PubMed GONUTS page
↑ ^5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 Thomas PD et al. (2007) Ontology annotation: mapping genomic regions to biological function. Curr Opin Chem Biol 11: 4-11 PubMed GONUTS page

[PMID:16823372-0] 1.0 ^1.1 Matsuyama A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol 24: 841-7 PubMed GONUTS page

[PMID:9858548-1] 2.0 ^2.1 ^2.2 Rudolph C et al. (1999) The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization. Mol Cell Biol 19: 241-50 PubMed GONUTS page

[PMID:9871115-2] Rudolph C et al. (1998) Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1. Curr Genet 34: 343-50 PubMed GONUTS page

[PMID:11333219-3] Mansour AA et al. (2001) Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors. Genetics 158: 77-85 PubMed GONUTS page

[PMID:17208035-4] 5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 Thomas PD et al. (2007) Ontology annotation: mapping genomic regions to biological function. Curr Opin Chem Biol 11: 4-11 PubMed GONUTS page

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SCHPO:MSH2

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