SALTY:TSX

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0009279	cell outer membrane		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005886	plasma membrane		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-KW
	GO:0046930	pore complex		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-KW
	GO:0005337	nucleoside transmembrane transporter activity		IEA: Inferred from Electronic Annotation		F	Source: InterPro
	GO:0015288	porin activity		IEA: Inferred from Electronic Annotation		F	Source: UniProtKB-KW
	GO:0009597	detection of virus		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0046718	entry of virus into host cell		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0006811	ion transport		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0022838	substrate-specific channel activity	PMID:9043137^[1]	IMP: Inferred from Mutant Phenotype		F	Fig. 4.& Table 2. The heterologous Tsx help to transport the deoxynucleoside. The strain with Tsx was fully sensitive to the antibiotic albicidin which depends on the Tsx channel for its permeation across the outer membrane. It functions as a substrate-specific channel.	complete
	GO:0031230	intrinsic to cell outer membrane	PMID:20149234^[2]	IDA: Inferred from Direct Assay		C	Additional File 1	complete
	GO:0006810	transport	PMID:9043137^[1]	IMP: Inferred from Mutant Phenotype		P	Fig. 4. The expressed S.typhimurium Tsx proteins facilitated the efficient uptake of the deoxynucleoside and there was no strong difference in the initial rate compared to E. Coli Tsx. This protein functions as a substrate-specific channel.	complete
	GO:0016021	integral to membrane	PMID:9043137^[1]	IMP: Inferred from Mutant Phenotype		C	Fig. 3 The tsx gene product can be separated from the cell envelope proteins.	complete
	GO:0005337	nucleoside transmembrane transporter activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003055	F
	GO:0005886	plasma membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C
	GO:0006810	transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P
	GO:0006811	ion transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0406	P
	GO:0009279	cell outer membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003055	C
	GO:0009279	cell outer membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR018013	C
	GO:0009279	cell outer membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0998	C
	GO:0009279	cell outer membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0040	C
	GO:0015288	porin activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0626	F
	GO:0015858	nucleoside transport	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003055	P
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C
	GO:0046930	pore complex	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0626	C
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Nieweg A & Bremer E (1997) The nucleoside-specific Tsx channel from the outer membrane of Salmonella typhimurium, Klebsiella pneumoniae and Enterobacter aerogenes: functional characterization and DNA sequence analysis of the tsx genes. Microbiology 143 ( Pt 2): 603-15 PubMed GONUTS page
↑ Chooneea D et al. (2010) Elucidation of the outer membrane proteome of Salmonella enterica serovar Typhimurium utilising a lipid-based protein immobilization technique. BMC Microbiol 10: 44 PubMed GONUTS page

[PMID:9043137-0] 1.0 ^1.1 ^1.2 Nieweg A & Bremer E (1997) The nucleoside-specific Tsx channel from the outer membrane of Salmonella typhimurium, Klebsiella pneumoniae and Enterobacter aerogenes: functional characterization and DNA sequence analysis of the tsx genes. Microbiology 143 ( Pt 2): 603-15 PubMed GONUTS page

[PMID:20149234-1] Chooneea D et al. (2010) Elucidation of the outer membrane proteome of Salmonella enterica serovar Typhimurium utilising a lipid-based protein immobilization technique. BMC Microbiol 10: 44 PubMed GONUTS page

[1]

[2]

Species (Taxon ID)	Salmonella typhimurium. (taxon:90371)
Gene Name(s)	tsx
Protein Name(s)	Nucleoside-specific channel-forming protein tsx
External Links
UniProt Identifier	TSX_SALTY
UniProt Accessions	P0A261, P40776,
EMBL	Z26657, AE006468,
PIR	S49159,
RefSeq	NP_459408.1,
Pfam	PF03502,

SALTY:TSX

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