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RAT:MANEA
Contents |
| Species (Taxon ID) | Rattus norvegicus (Rat). (taxon:10116) | |
| Gene Name(s) | Manea | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | MANEA_RAT | |
| UniProt Accessions | Q5GF25, O35390, | |
| EMBL | AF023657, AY599499, | |
| RefSeq | NP_542963.2, | |
| Ensembl | ENSRNOT00000011576, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000139 |
Golgi membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0134 |
C |
||||
| GO:0004569 |
glycoprotein endo-alpha-1,2-mannosidase activity |
IDA: Inferred from Direct Assay |
F |
FIG. 1. Thin-layer chromatographic identification of saccharides released by rat liver endomannoside from Man9GlcNAcH2 oligosaccharides with varying numbers of glucose residues. |
complete | |||
| GO:0004569 |
glycoprotein endo-alpha-1,2-mannosidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000351669 |
C |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0000139 |
Golgi membrane |
IDA: Inferred from Direct Assay |
C |
FIG. 8. Comparison of endomannosidase activity in Golgi, RER, and total microsomal (Micro) fractions from rat liver. |
complete | |||
| GO:0030134 |
ER to Golgi transport vesicle |
IDA: Inferred from Direct Assay |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||
| GO:0005797 |
Golgi medial cisterna |
IDA: Inferred from Direct Assay |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||
| GO:0000138 |
Golgi trans cisterna |
IDA: Inferred from Direct Assay |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||
| GO:0006491 |
N-glycan processing |
IDA: Inferred from Direct Assay |
P |
FIG. 4. Comparison of processing by endomannosidase of glycopeptides and their corresponding free oligosaccharides released by endo H digestion. |
complete | |||
| GO:0000139 |
Golgi membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0134 |
C |
||||
| GO:0004559 |
alpha-mannosidase activity |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0004569 |
glycoprotein endo-alpha-1,2-mannosidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000351669 |
C |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lubas WA & Spiro RG (1988) Evaluation of the role of rat liver Golgi endo-alpha-D-mannosidase in processing N-linked oligosaccharides. J Biol Chem 263: 3990-8 PubMed GONUTS page
- ↑ Lubas WA & Spiro RG (1987) Golgi endo-alpha-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme. J Biol Chem 262: 3775-81 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Torossi T et al. (2010) Endomannosidase undergoes phosphorylation in the Golgi apparatus. Glycobiology 20: 55-61 PubMed GONUTS page
- ↑ Spiro MJ et al. (1997) Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked oligosaccharide processing enzyme. J Biol Chem 272: 29356-63 PubMed GONUTS page
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