RAT:FGF2

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Species (Taxon ID)	Rattus norvegicus (Rat). (taxon:10116)
Gene Name(s)	Fgf2 ( synonyms: Fgf-2 )
Protein Name(s)	Heparin-binding growth factor 2 HBGF-2 Basic fibroblast growth factor bFGF
External Links
UniProt Identifier	FGF2_RAT
UniProt Accessions	P13109,
EMBL	M22427, X07285, U78079, X61697,
PIR	A31674,
RefSeq	NP_062178.1,
Ensembl	ENSRNOT00000023388,
Pfam	PF00167,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect
	GO:0010001	glial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0007275	multicellular organismal development	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0217	P
	GO:0007165	signal transduction	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0008284	positive regulation of cell proliferation	PMID:12000311^[2]	IDA: Inferred from Direct Assay		P
	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0010628	positive regulation of gene expression	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0007268	synaptic transmission	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0007243	intracellular protein kinase cascade	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0005163	nerve growth factor receptor binding	PMID:11161466^[4]	TAS: Traceable Author Statement		F
	GO:0008083	growth factor activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0339	F
	GO:0006355	regulation of transcription, DNA-dependent	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0008284	positive regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0005634	nucleus	PMID:7508717^[5]	IDA: Inferred from Direct Assay		C
	GO:0030154	cell differentiation	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0221	P
	GO:0043537	negative regulation of blood vessel endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0042060	wound healing	PMID:12533868^[6]	IEP: Inferred from Expression Pattern		P
	GO:0000189	MAPK import into nucleus	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P09038	P
	GO:0002042	cell migration involved in sprouting angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0060128	adrenocorticotropin hormone secreting cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction		F
	GO:0001525	angiogenesis	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0037	P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0000186	activation of MAPKK activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0030324	lung development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0045941	positive regulation of transcription	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	F
	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0045941	positive regulation of transcription	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:Q498D6	P
	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0060644	mammary gland epithelial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:Q498D6	F
	GO:0008083	growth factor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	F
	GO:0060045	positive regulation of cardiac muscle cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0006915	apoptosis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0001525	angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0060548	negative regulation of cell death	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0009790	embryo development	PMID:19476451^[9]	IMP: Inferred from Mutant Phenotype		P
	GO:0030308	negative regulation of cell growth	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0045766	positive regulation of angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0005737	cytoplasm	PMID:7508717^[5]	IDA: Inferred from Direct Assay		C
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:P21803	F
	GO:0017158	regulation of calcium ion-dependent exocytosis	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0060548	negative regulation of cell death	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P09038	P
	GO:0051781	positive regulation of cell division	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0497	P
	GO:0008285	negative regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0042660	positive regulation of cell fate specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	F
	GO:0060591	chondroblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0001759	organ induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0005245	voltage-gated calcium channel activity	PMID:12034732^[3]	IDA: Inferred from Direct Assay		F
	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0048864	stem cell development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction		P
	GO:0008083	growth factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002348	F
	GO:0046668	regulation of retinal cell programmed cell death	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0045597	positive regulation of cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	F
	GO:0010863	positive regulation of phospholipase C activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:P21803	P
	GO:0006700	C21-steroid hormone biosynthetic process	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0008201	heparin binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0358	F
	GO:0008083	growth factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002209	F
	GO:0051726	regulation of cell cycle	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0017134	fibroblast growth factor binding	PMID:12397076^[10]	IPI: Inferred from Physical Interaction		F
	GO:0045892	negative regulation of transcription, DNA-dependent	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0005615	extracellular space	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	C
	GO:0008284	positive regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000037694	P
	GO:0000186	activation of MAPKK activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0000189	MAPK import into nucleus	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0001525	angiogenesis	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0037	P
	GO:0001525	angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P09038	P
	GO:0001759	organ induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0001938	positive regulation of endothelial cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0002042	cell migration involved in sprouting angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	F
	GO:0005104	fibroblast growth factor receptor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	F
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:O35758	F
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:P21803	F
	GO:0005104	fibroblast growth factor receptor binding	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:Q498D6	F
	GO:0005163	nerve growth factor receptor binding	PMID:11161466^[4]	TAS: Traceable Author Statement		F
	GO:0005245	voltage-gated calcium channel activity	PMID:12034732^[3]	IDA: Inferred from Direct Assay		F
	GO:0005576	extracellular region	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	C
	GO:0005615	extracellular space	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	C
	GO:0005634	nucleus	PMID:7508717^[5]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:7508717^[5]	IDA: Inferred from Direct Assay		C
	GO:0006355	regulation of transcription, DNA-dependent	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0006661	phosphatidylinositol biosynthetic process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0006700	C21-steroid hormone biosynthetic process	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0006915	apoptosis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0007165	signal transduction	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0007243	intracellular protein kinase cascade	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0007268	synaptic transmission	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0007275	multicellular organismal development	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0217	P
	GO:0008083	growth factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002209	F
	GO:0008083	growth factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002348	F
	GO:0008083	growth factor activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0339	F
	GO:0008083	growth factor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	F
	GO:0008201	heparin binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0358	F
	GO:0008284	positive regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0008284	positive regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0008284	positive regulation of cell proliferation	PMID:12000311^[2]	IDA: Inferred from Direct Assay		P
	GO:0008285	negative regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:O35758	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:P21803	P
	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:10766846^[8]	IPI: Inferred from Physical Interaction	UniProtKB:Q498D6	P
	GO:0009790	embryo development	PMID:19476451^[9]	IMP: Inferred from Mutant Phenotype		P
	GO:0010001	glial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0010595	positive regulation of endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0010628	positive regulation of gene expression	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0010863	positive regulation of phospholipase C activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0017134	fibroblast growth factor binding	PMID:12397076^[10]	IPI: Inferred from Physical Interaction	RGD:620755	F
	GO:0017158	regulation of calcium ion-dependent exocytosis	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0021762	substantia nigra development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0030154	cell differentiation	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0221	P
	GO:0030308	negative regulation of cell growth	PMID:11856308^[1]	IDA: Inferred from Direct Assay		P
	GO:0030324	lung development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	F
	GO:0032958	inositol phosphate biosynthetic process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0042060	wound healing	PMID:12533868^[6]	IEP: Inferred from Expression Pattern		P
	GO:0042660	positive regulation of cell fate specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0043537	negative regulation of blood vessel endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0045597	positive regulation of cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0045766	positive regulation of angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0045766	positive regulation of angiogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0045892	negative regulation of transcription, DNA-dependent	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0045893	positive regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0045893	positive regulation of transcription, DNA-dependent	PMID:11557580^[7]	IDA: Inferred from Direct Assay		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0046668	regulation of retinal cell programmed cell death	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0048678	response to axon injury	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0048864	stem cell development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0051209	release of sequestered calcium ion into cytosol	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0051726	regulation of cell cycle	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0051781	positive regulation of cell division	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0497	P
	GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	PMID:12034732^[3]	IDA: Inferred from Direct Assay		P
	GO:0060045	positive regulation of cardiac muscle cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0060128	corticotropin hormone secreting cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0060548	negative regulation of cell death	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0060548	negative regulation of cell death	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P09038	P
	GO:0060591	chondroblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
	GO:0060644	mammary gland epithelial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000122227	P
	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000264498	P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Brucato S et al. (2002) Cell surface heparan sulfate proteoglycans: target and partners of the basic fibroblast growth factor in rat Sertoli cells. Eur J Biochem 269: 502-11 PubMed GONUTS page
↑ ^2.0 ^2.1 Delehedde M et al. (2002) Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts. Biochem J 366: 235-44 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Numakawa T et al. (2002) Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons. J Biol Chem 277: 28861-9 PubMed GONUTS page
↑ ^4.0 ^4.1 Clarke WE et al. (2001) Coordination of fibroblast growth factor receptor 1 (FGFR1) and fibroblast growth factor-2 (FGF-2) trafficking to nuclei of reactive astrocytes around cerebral lesions in adult rats. Mol Cell Neurosci 17: 17-30 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Eckenstein FP et al. (1994) Cellular distribution, subcellular localization and possible functions of basic and acidic fibroblast growth factors. Biochem Pharmacol 47: 103-10 PubMed GONUTS page
↑ ^6.0 ^6.1 Wang HJ et al. (2001) [A preliminary study on the changes of expression of PDGF-beta, PDGFR-beta, TGF-beta 1, TGFR, bFGF and its relationship with the wound age in wound healing]. Fa Yi Xue Za Zhi 17: 198-201, 204 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Carreras I et al. (2001) Functional components of basic fibroblast growth factor signaling that inhibit lung elastin gene expression. Am J Physiol Lung Cell Mol Physiol 281: L766-75 PubMed GONUTS page
↑ ^8.00 ^8.01 ^8.02 ^8.03 ^8.04 ^8.05 ^8.06 ^8.07 ^8.08 ^8.09 ^8.10 ^8.11 Konishi M et al. (2000) Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes. J Biol Chem 275: 12119-22 PubMed GONUTS page
↑ ^9.0 ^9.1 Unur E et al. (2009) Effect of anti-basic fibroblast growth factor (anti-bFGF) on in vitro embryonic development in rat. Anat Histol Embryol 38: 241-5 PubMed GONUTS page
↑ ^10.0 ^10.1 Claus P et al. (2003) Differential intranuclear localization of fibroblast growth factor-2 isoforms and specific interaction with the survival of motoneuron protein. J Biol Chem 278: 479-85 PubMed GONUTS page

[PMID:11856308-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Brucato S et al. (2002) Cell surface heparan sulfate proteoglycans: target and partners of the basic fibroblast growth factor in rat Sertoli cells. Eur J Biochem 269: 502-11 PubMed GONUTS page

[PMID:12000311-1] 2.0 ^2.1 Delehedde M et al. (2002) Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts. Biochem J 366: 235-44 PubMed GONUTS page

[PMID:12034732-2] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Numakawa T et al. (2002) Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons. J Biol Chem 277: 28861-9 PubMed GONUTS page

[PMID:11161466-3] 4.0 ^4.1 Clarke WE et al. (2001) Coordination of fibroblast growth factor receptor 1 (FGFR1) and fibroblast growth factor-2 (FGF-2) trafficking to nuclei of reactive astrocytes around cerebral lesions in adult rats. Mol Cell Neurosci 17: 17-30 PubMed GONUTS page

[PMID:7508717-4] 5.0 ^5.1 ^5.2 ^5.3 Eckenstein FP et al. (1994) Cellular distribution, subcellular localization and possible functions of basic and acidic fibroblast growth factors. Biochem Pharmacol 47: 103-10 PubMed GONUTS page

[PMID:12533868-5] 6.0 ^6.1 Wang HJ et al. (2001) [A preliminary study on the changes of expression of PDGF-beta, PDGFR-beta, TGF-beta 1, TGFR, bFGF and its relationship with the wound age in wound healing]. Fa Yi Xue Za Zhi 17: 198-201, 204 PubMed GONUTS page

[PMID:11557580-6] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Carreras I et al. (2001) Functional components of basic fibroblast growth factor signaling that inhibit lung elastin gene expression. Am J Physiol Lung Cell Mol Physiol 281: L766-75 PubMed GONUTS page

[PMID:10766846-7] 8.00 ^8.01 ^8.02 ^8.03 ^8.04 ^8.05 ^8.06 ^8.07 ^8.08 ^8.09 ^8.10 ^8.11 Konishi M et al. (2000) Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes. J Biol Chem 275: 12119-22 PubMed GONUTS page

[PMID:19476451-8] 9.0 ^9.1 Unur E et al. (2009) Effect of anti-basic fibroblast growth factor (anti-bFGF) on in vitro embryonic development in rat. Anat Histol Embryol 38: 241-5 PubMed GONUTS page

[PMID:12397076-9] 10.0 ^10.1 Claus P et al. (2003) Differential intranuclear localization of fibroblast growth factor-2 isoforms and specific interaction with the survival of motoneuron protein. J Biol Chem 278: 479-85 PubMed GONUTS page

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RAT:FGF2

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