RAT:ARRB2

From GONUTS

Jump to: navigation, search

Species (Taxon ID)	Rattus norvegicus (Rat). (taxon:10116)
Gene Name(s)	Arrb2
Protein Name(s)	Beta-arrestin-2 Arrestin beta-2
External Links
UniProt Identifier	ARRB2_RAT
UniProt Accessions	P29067,
EMBL	M91590, BC087578, U03627, AF051457,
PIR	A59279,
RefSeq	NP_037043.1,
IntAct	P29067,
Pfam	PF02752, PF00339,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0005905	coated pit		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0016023	cytoplasmic membrane-bounded vesicle		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005634	nucleus		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005886	plasma membrane		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0045211	postsynaptic membrane		IDA: Inferred from Direct Assay		C	Source: RGD
	GO:0030276	clathrin binding		TAS: Traceable Author Statement		F	Source: RGD
	GO:0001664	G-protein-coupled receptor binding		TAS: Traceable Author Statement		F	Source: RGD
	GO:0019904	protein domain specific binding		IPI: Inferred from Physical Interaction		F	Source: RGD
	GO:0002032	desensitization of G-protein coupled recept...		TAS: Traceable Author Statement		P	Source: RGD
	GO:0006897	endocytosis		IDA: Inferred from Direct Assay		P	Source: RGD
	GO:0007186	G-protein coupled receptor protein signalin...		IDA: Inferred from Direct Assay		P	Source: RGD
	GO:0009968	negative regulation of signal transduction		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0015031	protein transport		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0030817	regulation of cAMP biosynthetic process		TAS: Traceable Author Statement		P	Source: RGD
	GO:0030820	regulation of cAMP catabolic process		TAS: Traceable Author Statement		P	Source: RGD
	GO:0007600	sensory perception		IEA: Inferred from Electronic Annotation		P	Source: InterPro
	GO:0007165	signal transduction		IEA: Inferred from Electronic Annotation		P	Source: InterPro
	GO:0001664	G-protein-coupled receptor binding	PMID:11823056^[1]	TAS: Traceable Author Statement		F
	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin	PMID:11823056^[1]	TAS: Traceable Author Statement		P
	GO:0005515	protein binding	PMID:15361545^[2]	IPI: Inferred from Physical Interaction	RGD:2520	F
	GO:0005515	protein binding	PMID:16051150^[3]	IPI: Inferred from Physical Interaction	UniProtKB:Q2NL51	F
	GO:0005515	protein binding	PMID:16051150^[3]	IPI: Inferred from Physical Interaction	UniProtKB:Q9WV60	F
	GO:0005515	protein binding	PMID:18191226^[4]	IPI: Inferred from Physical Interaction	UniProtKB:P31749	F
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0005737	cytoplasm	PMID:16899567^[5]	IDA: Inferred from Direct Assay		C
	GO:0005886	plasma membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C
	GO:0005886	plasma membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0039	C
	GO:0005905	coated pit	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0168	C
	GO:0005905	coated pit	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0069	C
	GO:0006810	transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P
	GO:0006897	endocytosis	PMID:12600992^[6]	IDA: Inferred from Direct Assay		P
	GO:0007165	signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000698	P
	GO:0007165	signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014752	P
	GO:0007165	signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014753	P
	GO:0007165	signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017864	P
	GO:0007186	G-protein coupled receptor protein signaling pathway	PMID:157224^[7]	IDA: Inferred from Direct Assay		P
	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	PMID:1517224^[8]	IDA: Inferred from Direct Assay		P
	GO:0009968	negative regulation of signal transduction	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0734	P
	GO:0015031	protein transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0653	P
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016023	cytoplasmic membrane-bounded vesicle	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0088	C
	GO:0016323	basolateral plasma membrane	PMID:16899567^[5]	IDA: Inferred from Direct Assay		C
	GO:0019904	protein domain specific binding	PMID:12890920^[9]	IPI: Inferred from Physical Interaction	RGD:2520	F
	GO:0030276	clathrin binding	PMID:11823056^[1]	TAS: Traceable Author Statement		F
	GO:0030817	regulation of cAMP biosynthetic process	PMID:12399592^[10]	TAS: Traceable Author Statement		P
	GO:0030820	regulation of cAMP catabolic process	PMID:12399592^[10]	TAS: Traceable Author Statement		P
	GO:0031410	cytoplasmic vesicle	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0968	C
	GO:0031762	follicle-stimulating hormone receptor binding	PMID:16899567^[5]	IPI: Inferred from Physical Interaction	RGD:2632	F
	GO:0042699	follicle-stimulating hormone signaling pathway	PMID:16899567^[5]	IDA: Inferred from Direct Assay		P
	GO:0045211	postsynaptic membrane	PMID:1517224^[8]	IDA: Inferred from Direct Assay		C
	GO:0045211	postsynaptic membrane	PMID:157224^[7]	IDA: Inferred from Direct Assay		C
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Gurevich EV et al. (2002) Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development. Neuroscience 109: 421-36 PubMed GONUTS page
↑ Macey TA et al. (2004) Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons. Mol Pharmacol 66: 1635-42 PubMed GONUTS page
↑ ^3.0 ^3.1 Beaulieu JM et al. (2005) An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122: 261-73 PubMed GONUTS page
↑ Beaulieu JM et al. (2008) A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell 132: 125-36 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Marion S et al. (2006) G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells. J Endocrinol 190: 341-50 PubMed GONUTS page
↑ Wang J & Liu XJ (2003) A G protein-coupled receptor kinase induces Xenopus oocyte maturation. J Biol Chem 278: 15809-14 PubMed GONUTS page
↑ ^7.0 ^7.1 Horton JE et al. (1979) Partial purification of a bone-resorbing factor elaborated from human allogeneic cultures. Cell Immunol 43: 1-10 PubMed GONUTS page
↑ ^8.0 ^8.1 Attramadal H et al. (1992) Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. J Biol Chem 267: 17882-90 PubMed GONUTS page
↑ Kyoi S et al. (2003) Loss of intracellular dystrophin: a potential mechanism for myocardial reperfusion injury. Circ J 67: 725-7 PubMed GONUTS page
↑ ^10.0 ^10.1 Perry SJ et al. (2002) Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science 298: 834-6 PubMed GONUTS page

[PMID:11823056-0] 1.0 ^1.1 ^1.2 Gurevich EV et al. (2002) Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development. Neuroscience 109: 421-36 PubMed GONUTS page

[PMID:15361545-1] Macey TA et al. (2004) Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons. Mol Pharmacol 66: 1635-42 PubMed GONUTS page

[PMID:16051150-2] 3.0 ^3.1 Beaulieu JM et al. (2005) An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122: 261-73 PubMed GONUTS page

[PMID:18191226-3] Beaulieu JM et al. (2008) A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell 132: 125-36 PubMed GONUTS page

[PMID:16899567-4] 5.0 ^5.1 ^5.2 ^5.3 Marion S et al. (2006) G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells. J Endocrinol 190: 341-50 PubMed GONUTS page

[PMID:12600992-5] Wang J & Liu XJ (2003) A G protein-coupled receptor kinase induces Xenopus oocyte maturation. J Biol Chem 278: 15809-14 PubMed GONUTS page

[PMID:157224-6] 7.0 ^7.1 Horton JE et al. (1979) Partial purification of a bone-resorbing factor elaborated from human allogeneic cultures. Cell Immunol 43: 1-10 PubMed GONUTS page

[PMID:1517224-7] 8.0 ^8.1 Attramadal H et al. (1992) Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. J Biol Chem 267: 17882-90 PubMed GONUTS page

[PMID:12890920-8] Kyoi S et al. (2003) Loss of intracellular dystrophin: a potential mechanism for myocardial reperfusion injury. Circ J 67: 725-7 PubMed GONUTS page

[PMID:12399592-9] 10.0 ^10.1 Perry SJ et al. (2002) Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science 298: 834-6 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

RAT:ARRB2

Contents

Annotations

Notes

References

b

c

d

e

f

f cont.

g

m

n

p

p cont.

r

s

t

v

Personal tools

Namespaces

Variants

Views

Actions

Search

Navigation

Cacao

Journal Clubs

page contributors

Toolbox