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RAT:ACACA
Contents |
| Species (Taxon ID) | Rattus norvegicus (Rat). ([1]) | |
| Gene Name(s) | Acaca (synonyms: Acac) | |
| Protein Name(s) | Acetyl-CoA carboxylase 1
ACC1 ACC-alpha Biotin carboxylase | |
| External Links | ||
| EMBL | J03808 M26731 EF121986 EF121987 M26195 M26196 M26197 M55315 | |
| IPI | IPI00194102 IPI00567332 | |
| PIR | A35578 | |
| RefSeq | NP_071529.1 | |
| UniGene | Rn.163753 Rn.217177 Rn.44372 | |
| ProteinModelPortal | P11497 | |
| SMR | P11497 | |
| STRING | P11497 | |
| PhosphoSite | P11497 | |
| PRIDE | P11497 | |
| GeneID | 60581 | |
| KEGG | rno:60581 | |
| UCSC | NM_022193 | |
| CTD | 31 | |
| RGD | 621248 | |
| eggNOG | roNOG11411 | |
| GeneTree | ENSGT00550000074703 | |
| HOVERGEN | HBG005371 | |
| InParanoid | P11497 | |
| OrthoDB | EOG4X0MRD | |
| PhylomeDB | P11497 | |
| BRENDA | 6.4.1.2 | |
| NextBio | 612298 | |
| ArrayExpress | P11497 | |
| Genevestigator | P11497 | |
| GermOnline | ENSRNOG00000034013 | |
| GO | GO:0005829 GO:0005625 GO:0003989 GO:0005524 GO:0009374 GO:0004075 GO:0019900 GO:0046872 GO:0006084 GO:0006633 GO:0051289 GO:0042493 GO:0014070 | |
| InterPro | IPR013537 IPR011761 IPR013815 IPR013816 IPR001882 IPR011764 IPR005482 IPR000089 IPR005479 IPR005481 IPR000022 IPR011763 IPR011762 IPR013817 IPR016185 IPR011054 IPR011053 | |
| Gene3D | G3DSA:3.30.1490.20 G3DSA:3.30.470.20 G3DSA:3.40.50.20 | |
| KO | K11262 | |
| Pfam | PF08326 PF02785 PF00364 PF01039 PF00289 PF02786 | |
| SMART | SM00878 | |
| SUPFAM | SSF51230 SSF52440 SSF51246 | |
| PROSITE | PS50975 PS50979 PS00188 PS50968 PS50989 PS50980 PS00866 PS00867 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0001894 |
tissue homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
P |
Seeded From UniProt |
|||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
F |
Seeded From UniProt |
|||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0004075 |
biotin carboxylase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004075 |
biotin carboxylase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005625 |
soluble fraction |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005625 |
soluble fraction |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0006084 |
acetyl-CoA metabolic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0006629 |
lipid metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
P |
Seeded From UniProt |
|||
| GO:0006633 |
fatty acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006633 |
fatty acid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006633 |
fatty acid biosynthetic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008610 |
lipid biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0009374 |
biotin binding |
IMP: Inferred from Mutant Phenotype |
|
F |
Seeded From UniProt |
|||
| GO:0014070 |
response to organic cyclic compound |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016874 |
ligase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0019900 |
kinase binding |
IPI: Inferred from Physical Interaction |
RGD:70497 |
F |
Seeded From UniProt |
|||
| GO:0042493 |
response to drug |
IEP: Inferred from Expression Pattern |
|
P |
Seeded From UniProt |
|||
| GO:0044268 |
multicellular organismal protein metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
P |
Seeded From UniProt |
|||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0051289 |
protein homotetramerization |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0055088 |
lipid homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000048865 |
P |
Seeded From UniProt |
|||
| GO:0003989 |
acetyl-CoA carboxylase activity |
IDA: Inferred from Direct Assay |
F |
Figure 4 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Moura MA et al. (2001) Effect of cold acclimation on brown adipose tissue fatty acid synthesis in rats adapted to a high-protein, carbohydrate-free diet. Metabolism 50: 1493-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Rathman SC et al. (2003) Pharmacological biotin supplementation maintains biotin status and function in rats administered dietary carbamazepine. J Nutr 133: 2857-62 PubMed GONUTS page
- ↑ Harwood HJ Jr et al. (2003) Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. J Biol Chem 278: 37099-111 PubMed GONUTS page
- ↑ Crawford RM et al. (2005) A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase alpha1 in liver and lung. Biochem J 392: 201-9 PubMed GONUTS page
- ↑ Liang Y et al. (2006) The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment. Metabolism 55: 1411-9 PubMed GONUTS page
- ↑ Alberdi G et al. (2011) Changes in white adipose tissue metabolism induced by resveratrol in rats. Nutr Metab (Lond) 8: 29 PubMed GONUTS page
