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PSEAE:LASR
Contents |
| Species (Taxon ID) | Pseudomonas aeruginosa. (taxon:287) | |
| Gene Name(s) | lasR | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | LASR_PSEAE | |
| UniProt Accessions | P25084, Q51475, Q51476, | |
| EMBL | M59425, D30813, D30812, AE004091, | |
| PIR | A43660, S53692, S53693, | |
| RefSeq | NP_250121.1, | |
| PDB | 2UV0, 3IX3, 3IX4, 3IX8, 3JPU, | |
| Pfam | PF03472, PF00196, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0043565 |
sequence-specific DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0000160 |
two-component signal transduction system (phosphorelay) |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0009372 |
quorum sensing |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0000156 |
two-component response regulator activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
IMP: Inferred from Mutant Phenotype |
P |
Figure 7 shows that when cells contain a plasmid with a functional LasR and LasB, the LasR induces transcription of LasB transcripts. When there is a plasmid with a deletion mutation in LasR and still contains LasB, there is no transcription of LasB. Thus, showing that LasR positively regulates transcription. |
complete | |||
| GO:0009372 |
quorum sensing |
IDA: Inferred from Direct Assay |
P |
Figure 3a shows almost a two-fold increase in lasR expression under the presence of autoinducers, PAI-1 and PAI-2, showing that lasR is involved in quorum sensing in P. aeruginosa |
complete | |||
| GO:0000156 |
two-component response regulator activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0000160 |
two-component signal transduction system (phosphorelay) |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0009372 |
quorum sensing |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0043565 |
sequence-specific DNA binding |
IEA: Inferred from Electronic Annotation |
F |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gambello MJ & Iglewski BH (1991) Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J Bacteriol 173: 3000-9 PubMed GONUTS page
- ↑ Pesci EC et al. (1997) Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 179: 3127-32 PubMed GONUTS page
