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PMID:19000166
From GONUTS
Ceserani, T, Trofka, A, Gandotra, N and Nelson, T (2008) VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation.Plant J.
| Abstract | Abstract VH1/BRL2 is a receptor-like kinase of the BRI1 family with a role in vascular development. In developing Arabidopsis leaves, it is expressed first in ground cells and then becomes restricted to provascular and procambial cells as venation forms. We isolated proteins interacting with the activated (phosphorylated) cytoplasmic domain of VH1/BRL2, and found that most belong to three processes: proteasome activity, vesicle traffic and intracellular signal transduction. Included are two adaptor proteins, that we named VIT (VH1 interacting TPR containing protein) and VIK (VH1 interacting kinase), which are co-expressed in the same cells as VH1/BRL2 at two distinct time points in vein differentiation. Mutation of either adaptor or of VH1 results in vein pattern defects, and in alterations in response to auxin and brassinosteroids. We propose that these two adaptors facilitate the diversification and amplification of a ligand signal perceived by VH1/BRL2 in multiple downstream pathways affecting venation. |
| Links | PubMed Online version:10.1111/j.1365-313X.2008.03742.x |
Significance
Annotations
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